火炸药学报
火炸藥學報
화작약학보
CHINESE JOURNAL OF EXPLOSIVES & PROPELLANTS
2001年
2期
56-57
,共2页
丁三醇%羟基四氢呋喃%液相色谱法
丁三醇%羥基四氫呋喃%液相色譜法
정삼순%간기사경부남%액상색보법
用反相高效液相色谱法进行了1，2，4-丁三醇的分离条件选择实验，通过已知物对照保留值定性，进行了杂质峰的鉴定。由于各组分折光指数相近，用峰面积归一化法定量是可行的。研究表明：对于极性强，在较高温度下易分解的1，2，4-丁三醇的分析，用高效液相色谱法更为适宜。
用反相高效液相色譜法進行瞭1，2，4-丁三醇的分離條件選擇實驗，通過已知物對照保留值定性，進行瞭雜質峰的鑒定。由于各組分摺光指數相近，用峰麵積歸一化法定量是可行的。研究錶明：對于極性彊，在較高溫度下易分解的1，2，4-丁三醇的分析，用高效液相色譜法更為適宜。
용반상고효액상색보법진행료1，2，4-정삼순적분리조건선택실험，통과이지물대조보류치정성，진행료잡질봉적감정。유우각조분절광지수상근，용봉면적귀일화법정량시가행적。연구표명：대우겁성강，재교고온도하역분해적1，2，4-정삼순적분석，용고효액상색보법경위괄의。
The selective experiment of chromatographic separation condition of 1，2，4-butanetriol was done by Rp-HPLC. The chromatographic column was Micropak MCH-5(C18,5μm). The mobile phase was water. The detector was RID. The impurity peak identify was done by the comparision between retention time of an unknown sample and that of a known sample. Since the refractive index of compounds were similar, the area normalization method was practical.The research showed that for the 1，2，4-butanetriol which has strong polarity and is liable to decompose, HPLC was more adaptable than GC.
