CAJ | 학술논문

可以控制细胞粘附形状、大小的方法统称为细胞图案化技术.这些方法结合微纳米制备、表面化学、电化学和光化学等手段可以动态控制细胞的粘附、迁移、分化及其相互作用,为细胞生物学研究提供了一个新平台.本文介绍了二维平面细胞图案化的各种方法,并对其优缺点进行了总结,评述了细胞图案化技术在细胞生物学基础研究、组织工程以及基于细胞的生物传感器领域的应用.
가이공제세포점부형상、대소적방법통칭위세포도안화기술.저사방법결합미납미제비、표면화학、전화학화광화학등수단가이동태공제세포적점부、천이、분화급기상호작용,위세포생물학연구제공료일개신평태.본문개소료이유평면세포도안화적각충방법,병대기우결점진행료총결,평술료세포도안화기술재세포생물학기출연구、조직공정이급기우세포적생물전감기영역적응용.
The technologies that we call cell micropatterning allow the control of the shape and size of cell adhesion. Combination of micro/nano technology, surface chemistry, electrochemistry and photochemistry enables us to control the adhesion, migration, differentiation of cells and the interactions between different types of cells. These methodologies bring about a new platform for the studies of cell biology. A number of techniques for cell patterning and compares their advantages and disadvantages were reviewed in this article. The applications of cell micropatterning, including those for fundamental studies in cell biology, tissue engineering and cell-based biosensors were also discussed.