CAJ | 학술논문

目的采用Micro-Cr扫描采集人类拇指末节指骨三维微观数据并使用三维立体打印机,建立三维指骨支架材料模型,对仿生化、智能化组织工程支架材料的体外构建进行初步探讨.方法对成年男性新鲜拇指末节标本进行Micro-CT扫描,所得的原始DICOM数据为基础,通过Mimics软件三维处理得到宏观及微观仿生的三维打印STL文件,并通过三维打印机打印出指骨支架三维模型.结果采用Micro-CT扫描得到的数据用Mimics三维医学处理软件处理后,可直接用三维立体打印机快速成型构建仿生化、数字化组织工程指骨支架材料.结论基于Micro- CT及三维打印机的仿生化、智能化组织工程骨建模技术对治疗指骨毁损伤有重要的临床意义,且有良好的应用前景.
목적 채용Micro-Cr소묘채집인류무지말절지골삼유미관수거병사용삼유입체타인궤,건립삼유지골지가재료모형,대방생화、지능화조직공정지가재료적체외구건진행초보탐토.방법 대성년남성신선무지말절표본진행Micro-CT소묘,소득적원시DICOM수거위기출,통과Mimics연건삼유처리득도굉관급미관방생적삼유타인STL문건,병통과삼유타인궤타인출지골지가삼유모형.결과 채용Micro-CT소묘득도적수거용Mimics삼유의학처리연건처리후,가직접용삼유입체타인궤쾌속성형구건방생화、수자화조직공정지골지가재료.결론 기우Micro- CT급삼유타인궤적방생화、지능화조직공정골건모기술대치료지골훼손상유중요적림상의의,차유량호적응용전경.
Objective To prepare biomimetic,intelligent scaffold for tissue engineering of thumb distal phalanx using gathered three-dimensional (3D) data. Methods Distal phalanxes from fresh adult cadaver thumbs were subject to micro -CT scanning.The DICOM data from micro-CT scans were processed using Mimics software to form the macro and micro biomimetic 3D printing STL file.3D printer was then used to prim out a scaffold of a phalanx. Results The data acquired by micro-CT scanning can be rapidly prototyped after being edited with Mimics and directly used by 3D printing system to construet a biomimetic,intelligent scaffold.Conclusion Biomimetic,intelligent scaffold based on micro-CT and 3D printing has clinical significance in reconstruction of destructed thumbs.