国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2010年
14期
1729-1732
,共4页
重症甲型H1N1流感%静脉丙种球蛋白%治疗%儿童
重癥甲型H1N1流感%靜脈丙種毬蛋白%治療%兒童
중증갑형H1N1류감%정맥병충구단백%치료%인동
H1N1 influenza infection%Intravenous immunoglobulin%Therapy%Children
目的 探讨大剂量静脉丙种球蛋白治疗重症甲型H1N1流感患儿的临床价值.方法 回顾性总结本院2009年6-12月确诊的50例重症甲型H1N1流感病例,并依据是否使用大剂量静脉丙种球蛋白分为治疗组及对照组,总结两组患儿的临床资料,采用卡方检验统计两组患儿的临床改善情况,并结合文献进行分析.结果 当加用静脉丙种球蛋白静脉滴注后,治疗组经治疗后,体温下降10例,咳嗽11例,流涕8例,气促8例,肺部闻及啰音7例,喘鸣音8例,较治疗前及对照组有明显好转,各项指标比较差异有显著性(P<0.05).结论 大剂量静脉丙种球蛋白对重症甲型H1N1流感患儿临床症状改善方面具有明显疗效.
目的 探討大劑量靜脈丙種毬蛋白治療重癥甲型H1N1流感患兒的臨床價值.方法 迴顧性總結本院2009年6-12月確診的50例重癥甲型H1N1流感病例,併依據是否使用大劑量靜脈丙種毬蛋白分為治療組及對照組,總結兩組患兒的臨床資料,採用卡方檢驗統計兩組患兒的臨床改善情況,併結閤文獻進行分析.結果 噹加用靜脈丙種毬蛋白靜脈滴註後,治療組經治療後,體溫下降10例,咳嗽11例,流涕8例,氣促8例,肺部聞及啰音7例,喘鳴音8例,較治療前及對照組有明顯好轉,各項指標比較差異有顯著性(P<0.05).結論 大劑量靜脈丙種毬蛋白對重癥甲型H1N1流感患兒臨床癥狀改善方麵具有明顯療效.
목적 탐토대제량정맥병충구단백치료중증갑형H1N1류감환인적림상개치.방법 회고성총결본원2009년6-12월학진적50례중증갑형H1N1류감병례,병의거시부사용대제량정맥병충구단백분위치료조급대조조,총결량조환인적림상자료,채용잡방검험통계량조환인적림상개선정황,병결합문헌진행분석.결과 당가용정맥병충구단백정맥적주후,치료조경치료후,체온하강10례,해수11례,류체8례,기촉8례,폐부문급라음7례,천명음8례,교치료전급대조조유명현호전,각항지표비교차이유현저성(P<0.05).결론 대제량정맥병충구단백대중증갑형H1N1류감환인림상증상개선방면구유명현료효.
Objective To explore the clinic value of high-dose intravenous immunoglobulin for children with severe H1N1 influenza infection.Methods The data on 50 children with confirmed diagnosis who had been hospitalized during June to December 2009 were retrospectively analyzed.The children were divided equally into the high-dose group and the control group based on the dosage of immunoglobulin use.The clinical improvement was analyzed chi-square test and then compared with the reference of existing literatures.Results The baseline clinical features did not differ significantly between the two groups; however,there were significant differences in the improvement of symptoms,signs,and chest radiographic appearance between the high-dose group and the control group.Conclusions High-dose intravenous immunoglobulin is effective in improving the clinical symptoms and signs in children with severe H1N1 influenza infection.
