CAJ | 학술논문

[目的]探讨抗抑郁药物西酞普兰联合心理康复对高血压并抑郁症患者血压和生活质量的影响.[方法]106例伴有抑郁障碍的原发性高血压患者随机分为对照组和观察组各53例,对照组予常规治疗,观察组在对照组的基础上加用抗抑郁药物西酞普兰联合心理康复治疗,观察两组患者治疗前后血压、抑郁症状与生活质量的变化情况.[结果]治疗6周后,观察组总有效率为92.45％,对照组为71.70％,差异有显著性(P＜0.05);两组患者的收缩压、舒张压及HAMD评分均较治疗前明显下降(P＜0.05),观察组下降幅度明显大于对照组(P＜ 0.05);观察组患者治疗后躯体功能、心理功能、社会功能、物质功能及生活质量总分均明显升高(P＜0.05),对照组治疗前后变化不明显(P＞0.05).[结论]对原发性高血压病伴有抑郁症患者在常规治疗的基础上给予抗抑郁药物治疗与心理康复,能有效改善患者的生活质量,明显提高患者血压控制率.
[목적]탐토항억욱약물서태보란연합심리강복대고혈압병억욱증환자혈압화생활질량적영향.[방법]106례반유억욱장애적원발성고혈압환자수궤분위대조조화관찰조각53례,대조조여상규치료,관찰조재대조조적기출상가용항억욱약물서태보란연합심리강복치료,관찰량조환자치료전후혈압、억욱증상여생활질량적변화정황.[결과]치료6주후,관찰조총유효솔위92.45％,대조조위71.70％,차이유현저성(P＜0.05);량조환자적수축압、서장압급HAMD평분균교치료전명현하강(P＜0.05),관찰조하강폭도명현대우대조조(P＜ 0.05);관찰조환자치료후구체공능、심리공능、사회공능、물질공능급생활질량총분균명현승고(P＜0.05),대조조치료전후변화불명현(P＞0.05).[결론]대원발성고혈압병반유억욱증환자재상규치료적기출상급여항억욱약물치료여심리강복,능유효개선환자적생활질량,명현제고환자혈압공제솔.
[Objective]To discuss the effect of antidepressant drug citalopram combined with psychological rehabilitation treatment in reducing high blood pressure and affecting the quality of life (QOL) to the hypertension patients with depression.[Methods]106 primary hypertension patients with depressive disorder were selected,and randomly divided into two groups,53 cases in the control group were treated by conventional therapy,and on the basis of the treatment of the control group,53 cases in the observation group were treated by antidepressant medication citalopram combined with psychological rehabilitation,and then we observed their blood pressure,depressed symptom and the changes of the patients' QOL.[Results]After 6 weeks,the total effective rate of the observation group was 92.45％,and the control group was 71.70％,there was statistical significant difference between them(P＜ 0.05).All the patients' systolic pressure,diastolic pressure and HAMD score were declined a lot than before (P＜ 0.05),and the observation group was better than the control group(P＜ 0.05).The somatic function,mental function,social function,matter function and total points of the QOL in the observation group were all rising a lot(P＜ 0.05),but the control group had no change(P＞ 0.05).[Conclusion]For the primary hypertension patients with depressive disorder,on the basis of the conventional therapy,adding the antidepressant medication citalopram combined with psychological rehabilitation will ameliorate the patients' QOL and improve the control rate of the patients' s blood pressure.