中华骨科杂志
中華骨科雜誌
중화골과잡지
CHINESE JOURNAL OF ORTHOPAEDICS
2009年
7期
667-671
,共5页
彭雯佳%李小明%余铖%吴华%漆剑频%夏黎明%胡道予%胡军武%冯定义%邱丽%李宏莲
彭雯佳%李小明%餘鋮%吳華%漆劍頻%夏黎明%鬍道予%鬍軍武%馮定義%邱麗%李宏蓮
팽문가%리소명%여성%오화%칠검빈%하려명%호도여%호군무%풍정의%구려%리굉련
磁共振成像%股骨头%骨骺%缺血
磁共振成像%股骨頭%骨骺%缺血
자공진성상%고골두%골후%결혈
Magnetic resonance imaging%Femur head%Epiphyses%Ischemia
目的 比较动态Gadolinium(Gd)增强和常规Gd增强MR技术在早期缺血的股骨头骨骺中的灌注差异,并观察骨骺血管闭塞时生长板的血供.方法 28只2周龄乳猪,共56个髋关节,雄性12只,雌性16只;体重5～7 kg,平均6 kg;随机分为A、B、C、D组,每组7只.将A、B组乳猪的双髋关节极度外展固定30 min后,对A组行动态Gd增强FSPGR序列扫描,对B组行常规Gd增强SE T1WI序列扫描;行双髋关节外展体位的血管造影.之后让乳猪自由活动1 d,再采用双髋关节自然平放体位重复MR扫描.C、D组分别是A、B组的对照,即MR扫描前及扫描中双髋关节保持自然平放,C组行动态Gd增强扫描,D组行常规Gd增强扫描.最后将乳猪处死行组织学观察.结果 动态Gd增强MRI示:A组股骨头不同组织(除干骺端外)的强化率(ER)和强化速度(ES)均明显小于C组;A组生长板的ER和ES均小于干骺端,而C组生长板与干骺端的ER和ES值均无明显差异.常规Gd增强MRI示:B组股骨头各部分的ER与D组比较无明显下降.结论 对早期股骨头骨骺缺血的检测,动态Gd增强MRI技术比常规Gd增强SE T1WI技术更敏感.当骨骺血管闭塞时,生长板的血液灌注可能来自于干骺端.
目的 比較動態Gadolinium(Gd)增彊和常規Gd增彊MR技術在早期缺血的股骨頭骨骺中的灌註差異,併觀察骨骺血管閉塞時生長闆的血供.方法 28隻2週齡乳豬,共56箇髖關節,雄性12隻,雌性16隻;體重5～7 kg,平均6 kg;隨機分為A、B、C、D組,每組7隻.將A、B組乳豬的雙髖關節極度外展固定30 min後,對A組行動態Gd增彊FSPGR序列掃描,對B組行常規Gd增彊SE T1WI序列掃描;行雙髖關節外展體位的血管造影.之後讓乳豬自由活動1 d,再採用雙髖關節自然平放體位重複MR掃描.C、D組分彆是A、B組的對照,即MR掃描前及掃描中雙髖關節保持自然平放,C組行動態Gd增彊掃描,D組行常規Gd增彊掃描.最後將乳豬處死行組織學觀察.結果 動態Gd增彊MRI示:A組股骨頭不同組織(除榦骺耑外)的彊化率(ER)和彊化速度(ES)均明顯小于C組;A組生長闆的ER和ES均小于榦骺耑,而C組生長闆與榦骺耑的ER和ES值均無明顯差異.常規Gd增彊MRI示:B組股骨頭各部分的ER與D組比較無明顯下降.結論 對早期股骨頭骨骺缺血的檢測,動態Gd增彊MRI技術比常規Gd增彊SE T1WI技術更敏感.噹骨骺血管閉塞時,生長闆的血液灌註可能來自于榦骺耑.
목적 비교동태Gadolinium(Gd)증강화상규Gd증강MR기술재조기결혈적고골두골후중적관주차이,병관찰골후혈관폐새시생장판적혈공.방법 28지2주령유저,공56개관관절,웅성12지,자성16지;체중5～7 kg,평균6 kg;수궤분위A、B、C、D조,매조7지.장A、B조유저적쌍관관절겁도외전고정30 min후,대A조행동태Gd증강FSPGR서렬소묘,대B조행상규Gd증강SE T1WI서렬소묘;행쌍관관절외전체위적혈관조영.지후양유저자유활동1 d,재채용쌍관관절자연평방체위중복MR소묘.C、D조분별시A、B조적대조,즉MR소묘전급소묘중쌍관관절보지자연평방,C조행동태Gd증강소묘,D조행상규Gd증강소묘.최후장유저처사행조직학관찰.결과 동태Gd증강MRI시:A조고골두불동조직(제간후단외)적강화솔(ER)화강화속도(ES)균명현소우C조;A조생장판적ER화ES균소우간후단,이C조생장판여간후단적ER화ES치균무명현차이.상규Gd증강MRI시:B조고골두각부분적ER여D조비교무명현하강.결론 대조기고골두골후결혈적검측,동태Gd증강MRI기술비상규Gd증강SE T1WI기술경민감.당골후혈관폐새시,생장판적혈액관주가능래자우간후단.
Objective To investigate the perfusion difference of early ischaemia of the proximal femoral epiphysis by MRI between with dynamic Gadolinium (Gd)-enhanced technique and conventional Gd-enhanced technique, respectively, and to observe the contribution of metaphyseal vascularity to physeal per-fusion in epiphyseal vascular occlusion. Methods Fifty-six hips of 28 two-week-old piglets were studied. All piglets were randomly divided into four groups (group A, B, C and D), with 7 in each. In group A and B, MR1 was performed bilaterally on the hips in persistent hyperabduction for 30 min. The piglets of group A underwent dynamic Gd-enhanced FSPGR MR scan, and those of group B did Gd-enhanced SE T1WI MR scan. The piglets of group C underwent dynamic Gd-enhaneed FSPGR MR scan, and those of group D did Gd-enhanced SE T1WI MR scan respectively without hyperabduction. Results On dynamic Gd-euhanced MRI, the enhancement ratio (ER) and enhancement speed (ES) of various region of interest (ROI) (except the metaphysis) in group A were significantly lower than those in group C. However, on conventional Gd-en-hanced SE T1WI, no significant decrease in the ER of each ROI in group B was found, compared with the ER in group D. In group A, the ER and ES of the physis were less than those of metaphysis on dynamic Gd-enhanced MRI; however, in group C, the ER and ES of the physis were similar to those of metaphysis. Con-clusion Dynamic Gd-enhanced MRI has an advantage in the detection of early epiphyseal ischaemia, com-pared with conventional Gd-enhanced SE T1WI. Metaphyseal vessels might play an important role in physeal perfusion with epiphyseal vascular occlusion.
