CAJ | 학술논문

肿瘤多药耐药(MDR)是目前临床肿瘤化疗失败的主要原因之一.关于肿瘤多药耐药产生的机制有多种,针对这些不同的机制来研发相应的逆转药物则是目前解决临床耐药现象的主要途径.就目前国内外肿瘤多药耐药机制的研究进展作一综述.
종류다약내약(MDR)시목전림상종류화료실패적주요원인지일.관우종류다약내약산생적궤제유다충,침대저사불동적궤제래연발상응적역전약물칙시목전해결림상내약현상적주요도경.취목전국내외종류다약내약궤제적연구진전작일종술.
Multidrug resistance (MDR) is one of the main reasons for failure in clinical treatment of cancer.A variety of different mechanisms involves in the occurrence and during the development of MDR.Exploiting the corresponding reversal drugs according to the mechanisms is the major route of solving MDR problems clinically.In this article,research of MDR mechanisms,at home and abroad is reviewed.