中国医药
中國醫藥
중국의약
CHINA MEDICINE
2011年
10期
1159-1160
,共2页
心绞痛,不稳定型%低分子量肝素%银杏达莫
心絞痛,不穩定型%低分子量肝素%銀杏達莫
심교통,불은정형%저분자량간소%은행체막
Angina pectoris,unstable%Low-molecule heparin%Ginkgo dipyidamolum
目的 探讨低分子肝素( LMWH)联合银杏达莫注射液治疗不稳定型心绞痛的疗效。方法 选择2006年3月至2010年3月不稳定型心绞痛患者175例,完全随机分为治疗组(58例)、对照Ⅰ组(52例)和对照Ⅱ组(65例)。在常规治疗的基础上,治疗组应用LMWH联合银杏达莫注射液治疗,对照Ⅰ组应用LMWH治疗,对照Ⅱ组应用银杏达莫注射液治疗,疗程均为2周。比较3组临床症状改善、心电图缺血改善及复合终点事件发生情况。结果 治疗后治疗组临床症状改善总有效率、心电图缺血改善总有效率、复合终点事件发生率方面明显优于对照Ⅰ组和对照Ⅱ组[分别为82.76%( 48/58)比65.38% (34/52)、63.08% (41/65),77.59% (45/58)比55.77% (29/52)、53.85%(35/65),18.97%(11/58)比36.54%( 19/52)、35.38%(23/65)],差异有统计学意义(P<0.05或P<0.01)。结论 LMWH联合银杏达莫注射液可以明显改善不稳定型心绞痛患者心肌供血,缓解临床症状,疗效明显优于单用LMWH或银杏达莫注射液。
目的 探討低分子肝素( LMWH)聯閤銀杏達莫註射液治療不穩定型心絞痛的療效。方法 選擇2006年3月至2010年3月不穩定型心絞痛患者175例,完全隨機分為治療組(58例)、對照Ⅰ組(52例)和對照Ⅱ組(65例)。在常規治療的基礎上,治療組應用LMWH聯閤銀杏達莫註射液治療,對照Ⅰ組應用LMWH治療,對照Ⅱ組應用銀杏達莫註射液治療,療程均為2週。比較3組臨床癥狀改善、心電圖缺血改善及複閤終點事件髮生情況。結果 治療後治療組臨床癥狀改善總有效率、心電圖缺血改善總有效率、複閤終點事件髮生率方麵明顯優于對照Ⅰ組和對照Ⅱ組[分彆為82.76%( 48/58)比65.38% (34/52)、63.08% (41/65),77.59% (45/58)比55.77% (29/52)、53.85%(35/65),18.97%(11/58)比36.54%( 19/52)、35.38%(23/65)],差異有統計學意義(P<0.05或P<0.01)。結論 LMWH聯閤銀杏達莫註射液可以明顯改善不穩定型心絞痛患者心肌供血,緩解臨床癥狀,療效明顯優于單用LMWH或銀杏達莫註射液。
목적 탐토저분자간소( LMWH)연합은행체막주사액치료불은정형심교통적료효。방법 선택2006년3월지2010년3월불은정형심교통환자175례,완전수궤분위치료조(58례)、대조Ⅰ조(52례)화대조Ⅱ조(65례)。재상규치료적기출상,치료조응용LMWH연합은행체막주사액치료,대조Ⅰ조응용LMWH치료,대조Ⅱ조응용은행체막주사액치료,료정균위2주。비교3조림상증상개선、심전도결혈개선급복합종점사건발생정황。결과 치료후치료조림상증상개선총유효솔、심전도결혈개선총유효솔、복합종점사건발생솔방면명현우우대조Ⅰ조화대조Ⅱ조[분별위82.76%( 48/58)비65.38% (34/52)、63.08% (41/65),77.59% (45/58)비55.77% (29/52)、53.85%(35/65),18.97%(11/58)비36.54%( 19/52)、35.38%(23/65)],차이유통계학의의(P<0.05혹P<0.01)。결론 LMWH연합은행체막주사액가이명현개선불은정형심교통환자심기공혈,완해림상증상,료효명현우우단용LMWH혹은행체막주사액。
Objective To study the therapeutic effect of low-molecule heparin (LMWH) and Ginkgo-dipyidamolum injection for unstable angina (UA). Methods One hundred and seventy-five cases with UA were chosen from March 2006 to March 2010, completely randomly divided into treatment group (58 cases) and control group Ⅰ (52 cases) and control group Ⅱ (65 cases). On the basis of routine therapy, control and treatment groups for UA patients were established, and for experimental group, 58 patients were treated with both LMWH and Ginkgo-dipyidamolum injection. Results Statistically,compared with control group, the treatment of experimental group is more effective on aspects as follows: easing clinical symptoms, allaying myocardial ischemia diagnosed by electrocardiogram, and preventing composite of non-fatal stroke, myocardial infarction and cardiovascular death[82.76% (48/58 ) vs 65.38% (34/52) ,63.08% (41/65) ;77.59% (45/58) vs 55.77% (29/52) ,53.85% (35/65) ;18.97% (11/58)vs36.54%(19/52),35.38%(23/65),P<0. 05,P<0.01]. Conclusion LMWH and Ginkgo-dipyidamolum injection are more effective than that of either LMWH or Ginkgo-dipyidamolum injection on abirritating myocardial blooding and relieving clinical symptom.