CAJ | 학술논문

目的探讨CO:激光联合磷[32P]酸钠盐敷贴治疗顽固性瘢痕疙瘩的效果.方法 2001至2006年,对122例151个经过2种或2种以上方法治疗后复发的顽固性瘢痕疙瘩,采用下述方法:①连续波CO2激光去除增生性瘢痕组织,超脉冲CO2激光治疗新鲜肉芽组织；②磷[32P]酸钠盐敷贴:创面愈合后,依据患者年龄、个体差异、身体状况,以及瘢痕厚度、大小和不同部位,给予磷[32P]酸钠盐敷贴0.5～1 MBQ/cm2,时间为72～96 h,每1～2个月1次,连续用2～3次.结果 122例151个顽同性瘢痕疙瘩,显效为111个,有效为40个.不良反应包括色素沉着21处、色素脱失32处.经随访2～6年,无一例复发.结论 CO2激光联合磷[32P]酸钠盐敷贴治疗顽固性瘢痕疙瘩是一种较安全有效的方法.
목적 탐토CO:격광연합린[32P]산납염부첩치료완고성반흔흘탑적효과.방법 2001지2006년,대122례151개경과2충혹2충이상방법치료후복발적완고성반흔흘탑,채용하술방법:①련속파CO2격광거제증생성반흔조직,초맥충CO2격광치료신선육아조직；②린[32P]산납염부첩:창면유합후,의거환자년령、개체차이、신체상황,이급반흔후도、대소화불동부위,급여린[32P]산납염부첩0.5～1 MBQ/cm2,시간위72～96 h,매1～2개월1차,련속용2～3차.결과 122례151개완동성반흔흘탑,현효위111개,유효위40개.불량반응포괄색소침착21처、색소탈실32처.경수방2～6년,무일례복발.결론 CO2격광연합린[32P]산납염부첩치료완고성반흔흘탑시일충교안전유효적방법.
Objective To investigate the efficacy of CO2 laser combined with32P -patch contact brachyradiotherapy for the treatment of keloids.Methods From 2001 to 2006,121 cases with 151keloids,which reoccurred after treatment with more than 2 methods,underwent continuous CO2 laser treatment to remove the hypertrophic scar tissue,following by ultra-pulse CO2 laser to treat the fresh granulation tissue.After wound healing,32P-patch contact brachyradiotherapy was used for the lesion,0.5-1 MBQ/cm2 for 72-96 hours,every 1-2 months.2-3 treatment were applied.Results Among the 151keloids,good result was achieved in 111 keloids,and effective result in 40 keloids.Adverse effect included hyperpigmentation in 21 lesions and hypopigmentation in 32 lesions.The patients were followed up for 2-6 years without relapse.Conclusion CO2 laser combined with 32P-patch contact brachyradiotherapy is an effective and safe method for the treatment of recalcitrant keloids.