抗生素9792A和B的分离与结构鉴定及抗结核活性研究
항생소9792A화B적분리여결구감정급항결핵활성연구
Isolation, structure identification and anti-TB activity of antibiotics 9792A and B
  • 万方数据
    中国抗生素杂志 중국항생소잡지
    CHINESE JOURNAL OF ANTIBIOTICS
    2010年 5期 346-348,356 ,共4页

    樊秀勇%郝雪秦%姜威%刘伟%余利岩%张月琴%肖春玲%司书毅

    번수용%학설진%강위%류위%여리암%장월금%초춘령%사서의

    结核分枝杆菌%Pimprinine%Pimprinethine%9792A%9792B 結覈分枝桿菌%Pimprinine%Pimprinethine%9792A%9792B
    결핵분지간균%Pimprinine%Pimprinethine%9792A%9792B
    在筛选新型抗结核抗生素过程中,对一株阳性链霉菌9792的发酵产物进行了分离纯化,获得了两个活性组分9792A和B.经光谱分析,确定9792A为pimprinethine,9792B为pimprinine.9792A和B抗结核分枝杆菌H37Rv的MIC分别为32μg/mL和16μg/mL,其确切抗结核活性属首次报道.
    재사선신형항결핵항생소과정중,대일주양성련매균9792적발효산물진행료분리순화,획득료량개활성조분9792A화B.경광보분석,학정9792A위pimprinethine,9792B위pimprinine.9792A화B항결핵분지간균H37Rv적MIC분별위32μg/mL화16μg/mL,기학절항결핵활성속수차보도.
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