CAJ | 학술논문

糖组学在后基因组时代日益受到关注,糖蛋白的比较研究已成为肿瘤研究的热点,凝集素相关的糖链富集、分析技术也得到了广泛发展,运用于研究细胞、体液、组织的蛋白质糖链改变.有别于其他糖富集、鉴定技术,凝集素对不同构型的糖有特异性识别能力,可使糖及其缀合物在避免破坏糖链的前提下得到鉴定.
당조학재후기인조시대일익수도관주,당단백적비교연구이성위종류연구적열점,응집소상관적당련부집、분석기술야득도료엄범발전,운용우연구세포、체액、조직적단백질당련개변.유별우기타당부집、감정기술,응집소대불동구형적당유특이성식별능력,가사당급기철합물재피면파배당련적전제하득도감정.
With the emergence of glycomies in the post-genome era,various lectin-related techniques have been developed to analyse the glycoproteins from cells,body fluids and tissues in comparative glycoprotein studies of cancer research.Compared to other techniques of glycan enrichment and identification,lectin-based techniques can sort and identify glycoconjugates without glycan modification,ascribed to the specific affinity of lectins and their corresponding glycans.