CAJ | 학술논문

高蛋白饮食与糖代谢关系复杂,尚无定论.多数研究认为高蛋白饮食可改善血精控制,是一种有效的糖尿病饮食干预疗法,但另有流行病学调查认为其能增加2型糖尿病的发病风险.高蛋白饮食通过糖异生、糖摄取改变胰岛素敏感性,并能增加餐后胰岛素释放.其促胰岛素分泌作用与进餐后分泌的胃肠道激素--ghrelin、胰高血糖素样肽-1(GLP-1)有关,后两者可分别通过抑制或促进胰岛素释放来影响糖代谢.长期高蛋白饮食的有效性和安全性尚需进一步研究.
고단백음식여당대사관계복잡,상무정론.다수연구인위고단백음식가개선혈정공제,시일충유효적당뇨병음식간예요법,단령유류행병학조사인위기능증가2형당뇨병적발병풍험.고단백음식통과당이생、당섭취개변이도소민감성,병능증가찬후이도소석방.기촉이도소분비작용여진찬후분비적위장도격소--ghrelin、이고혈당소양태-1(GLP-1)유관,후량자가분별통과억제혹촉진이도소석방래영향당대사.장기고단백음식적유효성화안전성상수진일보연구.
The relationship between high-protein diet and glucose metabolism is complex and uncertain. Recently, many researches have shown high protein intake can improve glycaemic control, and seems to be an effective dietary intervention of diabetes. But other researches indicate it might increase the incidence of type 2 diabetes. The intake of proteins at the expense of carbohydrates changes insulin sensitivity by gluconeogenesis and glucose uptake,and augments postprandial insulin secretion. The insulintropic effect of highprotein diet may involve ghrelin and glucagon-like peptide-1 (GLP-1),which have effect on glucose metabolism by suppressing or stimulating insulin secretion. The long term efficacy and safety of high-protein diet need further study.