国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2010年
4期
355-356
,共2页
朱砂七蒽醌%亚硝酸钠%亚硝胺
硃砂七蒽醌%亞硝痠鈉%亞硝胺
주사칠은곤%아초산납%아초알
Polygonum Cillinerve (Nakai) Ohwi%Anthraquinone%Sodium nitrite%Nitrosamine
目的 考察朱砂七总蒽醌对亚硝化反应的抑制活性.方法 以硫酸、氯仿为溶剂从朱砂七中提取总蒽醌,在模拟人体胃液的条件下,采用分光光度法测定朱砂七蒽醌(ZSQEK)对亚硝酸盐的清除能力和对亚硝胺合成的阻断能力.结果 ZSQEK对亚硝胺合成的阻断能力和对亚硝酸钠的清除能力与浓度呈相关关系,最大清除率为53.5%,最大阻断率为71.3%.结论 ZSQEK对亚硝化反应具有较强的抑制作用.
目的 攷察硃砂七總蒽醌對亞硝化反應的抑製活性.方法 以硫痠、氯倣為溶劑從硃砂七中提取總蒽醌,在模擬人體胃液的條件下,採用分光光度法測定硃砂七蒽醌(ZSQEK)對亞硝痠鹽的清除能力和對亞硝胺閤成的阻斷能力.結果 ZSQEK對亞硝胺閤成的阻斷能力和對亞硝痠鈉的清除能力與濃度呈相關關繫,最大清除率為53.5%,最大阻斷率為71.3%.結論 ZSQEK對亞硝化反應具有較彊的抑製作用.
목적 고찰주사칠총은곤대아초화반응적억제활성.방법 이류산、록방위용제종주사칠중제취총은곤,재모의인체위액적조건하,채용분광광도법측정주사칠은곤(ZSQEK)대아초산염적청제능력화대아초알합성적조단능력.결과 ZSQEK대아초알합성적조단능력화대아초산납적청제능력여농도정상관관계,최대청제솔위53.5%,최대조단솔위71.3%.결론 ZSQEK대아초화반응구유교강적억제작용.
Objective To study inhibitory activity of anthraquinone in Polygonum Cillinerve(Nakai) Ohwi (anthraquinone in PCO) to nitrosation. Methods Anthraquinone was extracted from Polygonum Cillinerve(Nakai) Ohwi with sulfuric acid and chloroform as solvents. The capability of scavenging sodium nitrite and disconnecting nitrosamine synthesis with anthraquinone in PCO were determined by spectrophotometry under simulated human gastric juice. Results Both the sodium nitrite scavenging rate and the nitrosamine synthesis disconnecting rate showed the positive correlation with the concentration of anthraquinone in PCO. The strongest capability of scavenging sodium nitrite was 53.5%, and the strongest capability of disconnecting nitrosamine synthesis was 71.3%. Conclusion Anthraquinone in PCO had strong capability of scavenging sodium nitrite and disconnecting nitrosamine synthesis.
