中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2008年
10期
1655-1656
,共2页
肾功能衰竭,急性%心钠素%炎性反应
腎功能衰竭,急性%心鈉素%炎性反應
신공능쇠갈,급성%심납소%염성반응
Kidney failure,acute%Atrial natriuretic peptide%Inflammatory response
目的 探讨急性肾功能衰竭患者慢性炎性反应与心钠素的关系.方法 测定75例急性肾功能衰竭患者慢性炎性指标血C-反应蛋白(CRP)、IL-6、TNF-α及心钠素,分析它们之间的关系.结果 有62.7%急性肾功能衰竭患者心钠素超过正常参考值,心钠素升高组血清CBP、IL-6显著高于心钠素降低组(均P<0.05);血心钠素与CRP(P<0.01)、IL-6及TNF-α呈正相关(P<0.05).结论 急性肾功能衰竭患者存在炎性反应,可能引起心钠素等代谢异常.
目的 探討急性腎功能衰竭患者慢性炎性反應與心鈉素的關繫.方法 測定75例急性腎功能衰竭患者慢性炎性指標血C-反應蛋白(CRP)、IL-6、TNF-α及心鈉素,分析它們之間的關繫.結果 有62.7%急性腎功能衰竭患者心鈉素超過正常參攷值,心鈉素升高組血清CBP、IL-6顯著高于心鈉素降低組(均P<0.05);血心鈉素與CRP(P<0.01)、IL-6及TNF-α呈正相關(P<0.05).結論 急性腎功能衰竭患者存在炎性反應,可能引起心鈉素等代謝異常.
목적 탐토급성신공능쇠갈환자만성염성반응여심납소적관계.방법 측정75례급성신공능쇠갈환자만성염성지표혈C-반응단백(CRP)、IL-6、TNF-α급심납소,분석타문지간적관계.결과 유62.7%급성신공능쇠갈환자심납소초과정상삼고치,심납소승고조혈청CBP、IL-6현저고우심납소강저조(균P<0.05);혈심납소여CRP(P<0.01)、IL-6급TNF-α정정상관(P<0.05).결론 급성신공능쇠갈환자존재염성반응,가능인기심납소등대사이상.
Objective To investigate the pathway that inflammatory response in acute renal failure effect on cardiovascular system by analyzing the relationship between inflammatory indices and atrial natriuretic peptide in acute renal failure patients. Methods Atrial natriuretie peptide and the serum inflammatory indices including C-reactive protein(CRP) ,interleukin-6(IL-6) and tumor necrotic factor-a(TNF-α) were measured in 75 patients with acute re-nal failure,the relationship among them was analyzed. Results 62.7% of all patients presented increased ANP lev-els. The serum CRP, IL-6 levels in increased atrial natriuretic peptide group were significantly higher than those in lower atrial natriuretic peptide group. Atrial natduretic peptide in uremia positively correlated with CRP( P<0.01),IL-6 and TNF-α(P<0.05). Conclusion There is inflammatory state in acute renal failure patients, inflammation may have effects on cardiovascular system by leading to metabolic disorder of atrial natriuretic peptide.
