CAJ | 학술논문

目的评价不同类型激光治疗寻常痤疮的疗效和安全性,以便为临床应用选择最佳方案提供依据.方法采用Cochrane系统评价的方法,计算机检索Medline、Embase、Cochrane对照实验注册资料库、中国生物医学文献数据库、中文科技期刊数据库、中国期刊全文数据库,检索时间截至2009年6月,纳入中英文激光治疗寻常痤疮的随机对照实验(RCT).结果共纳入符合标准的论文12篇,临床治疗367例,由于缺乏临床同质性,只能进行描述性分析.各型激光治疗寻常痤疮,炎症性皮损计数改善明显,不良反应限于治疗部位的暂时性红斑水肿及可以耐受的与治疗相关的疼痛.结论各型激光治疗寻常痤疮安全、有效、便利.有局部不良反应.需进行更多高质量、大样本的随机对照实验,以证实激光治疗寻常痤疮的作用和地位.
목적 평개불동류형격광치료심상좌창적료효화안전성,이편위림상응용선택최가방안제공의거.방법 채용Cochrane계통평개적방법,계산궤검색Medline、Embase、Cochrane대조실험주책자료고、중국생물의학문헌수거고、중문과기기간수거고、중국기간전문수거고,검색시간절지2009년6월,납입중영문격광치료심상좌창적수궤대조실험(RCT).결과 공납입부합표준적논문12편,림상치료367례,유우결핍림상동질성,지능진행묘술성분석.각형격광치료심상좌창,염증성피손계수개선명현,불량반응한우치료부위적잠시성홍반수종급가이내수적여치료상관적동통.결론 각형격광치료심상좌창안전、유효、편리.유국부불량반응.수진행경다고질량、대양본적수궤대조실험,이증실격광치료심상좌창적작용화지위.
Objective To assess the efficacy and safety of various spectrum lasers in the treatment of acne vulgaris. Methods Based on the principles and methods of Cochrane systematic reviews, we searched the Cochrane Library (2009, 6 issues), PubMcd, Embase, China Biomedical Literature Database, China Journal Full Text Database, Chinese Scientific Journals Full Text Database. Retrieval time was up to June, 2009. Randomized controlled trials (RCTs) of lasers for acne vulgaris were included. Results Twelve RCTs totaling 367 patients were included. Because the lack of clinical homogeneity, only descriptive analysis was conducted. Acne lesion counts improved significantly with laser therapy. Adverse effects were limited to transient erythema and edema at treatment sites. Treatment-related pains were well tolerated. Conclusions Current evidence demonstrates that all type lasers in treating acne vulgaris is safe and efficacy. However, higher quality RCT research would be needed to verify the effects and status of lasers on acne vulgaris.