中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
6期
438-441
,共4页
罗知卫%李建南%姜德咏%李曦%李晓静%彭婷
囉知衛%李建南%薑德詠%李晞%李曉靜%彭婷
라지위%리건남%강덕영%리희%리효정%팽정
角膜炎,感染性%角膜移植%药物治疗%手术治疗
角膜炎,感染性%角膜移植%藥物治療%手術治療
각막염,감염성%각막이식%약물치료%수술치료
keratitis%infectious%keratoplasty%drug therapy
目的 分析183例(187眼)感染性角膜炎的病因、治疗方法和结果.方法 明确角膜感染的种类,采用药物和手术进行治疗,治疗后观察临床效果.结果 单眼发病179例,双眼发病4例.发病年龄为1～80岁,平均(52.75±15.08)岁.男117例,女66例.真菌性角膜溃疡84眼(44.92%),细菌性角膜溃疡28眼(14.97%),病毒性角膜炎14眼(7.49%),细菌真菌混合感染5眼(2.67%),病因不确定56眼(29.95%).单纯药物治疗者118眼(63.10%),清创联合结膜瓣遮盖术24眼(12.83%),清创联合羊膜移植结膜瓣遮盖术19眼(10.16%),治疗性角膜移植术18眼(9.63%)(其中穿透性角膜移植术16眼,板层角膜移植术2眼),泪囊鼻腔吻合术5眼(2.67%),眼内容摘除术5眼(2.67%),其中2眼为羊膜移植失败者.结论 真菌性角膜炎是感染性角膜炎的主要病因,局部清创联合安尔碘Ⅲ稀释液冲洗及药物治疗对大部分感染性角膜炎有效,部分患者仍需要手术治疗.
目的 分析183例(187眼)感染性角膜炎的病因、治療方法和結果.方法 明確角膜感染的種類,採用藥物和手術進行治療,治療後觀察臨床效果.結果 單眼髮病179例,雙眼髮病4例.髮病年齡為1～80歲,平均(52.75±15.08)歲.男117例,女66例.真菌性角膜潰瘍84眼(44.92%),細菌性角膜潰瘍28眼(14.97%),病毒性角膜炎14眼(7.49%),細菌真菌混閤感染5眼(2.67%),病因不確定56眼(29.95%).單純藥物治療者118眼(63.10%),清創聯閤結膜瓣遮蓋術24眼(12.83%),清創聯閤羊膜移植結膜瓣遮蓋術19眼(10.16%),治療性角膜移植術18眼(9.63%)(其中穿透性角膜移植術16眼,闆層角膜移植術2眼),淚囊鼻腔吻閤術5眼(2.67%),眼內容摘除術5眼(2.67%),其中2眼為羊膜移植失敗者.結論 真菌性角膜炎是感染性角膜炎的主要病因,跼部清創聯閤安爾碘Ⅲ稀釋液遲洗及藥物治療對大部分感染性角膜炎有效,部分患者仍需要手術治療.
목적 분석183례(187안)감염성각막염적병인、치료방법화결과.방법 명학각막감염적충류,채용약물화수술진행치료,치료후관찰림상효과.결과 단안발병179례,쌍안발병4례.발병년령위1～80세,평균(52.75±15.08)세.남117례,녀66례.진균성각막궤양84안(44.92%),세균성각막궤양28안(14.97%),병독성각막염14안(7.49%),세균진균혼합감염5안(2.67%),병인불학정56안(29.95%).단순약물치료자118안(63.10%),청창연합결막판차개술24안(12.83%),청창연합양막이식결막판차개술19안(10.16%),치료성각막이식술18안(9.63%)(기중천투성각막이식술16안,판층각막이식술2안),루낭비강문합술5안(2.67%),안내용적제술5안(2.67%),기중2안위양막이식실패자.결론 진균성각막염시감염성각막염적주요병인,국부청창연합안이전Ⅲ희석액충세급약물치료대대부분감염성각막염유효,부분환자잉수요수술치료.
Objective To analyse the pathogenesis,treatment and result of 183 in-patient with infectious keratitis form January 2004 to December 2009. Methods Clinical manifestations, pathogenesis results was used to clear different corneal infections. Operations and drugs were used to treat these diseases.and results were observed during whole in-patient period. Results All infectious eyes were seen in 179 cases with one eye affected and 4 cases with both eyes affected,the age between 1～80 years,mean age 52. 75 years;male 117 cases( 119 eyes) and female 66 cases(68 eyes). 84 eyes with fungal infection,28 eyes with bacterial infection, 14 eyes with viral infection,5 eyes with mixed infection and 56 eyes with unknown infection;118 eyes received drug treatment (63. 10% ) ,24 eyes received local debridement combined with conjunctival flap microsurgery (12. 83% ), 17 eyes received local debridement combined with amniotic membrane transplantation and conjunctival flap microsurgery (9. 09% ) , 18 eyes received keratoplasty (9. 63% )(16 eyes with penetrating keratoplasty. 2 eyes with lamellar keratoplasty) , 5 eyes received dacryocystorhinostomy (2. 67% ) and 5 eyes with enucleation (2. 67% ). Conclusion Fungal keratitis is the main cause for infectious keratitis; early diagnosis and early drug therapy are effective in most patients, however, some patients need surgery.
