CAJ | 학술논문

目的应用光学成像系统一前段OCT(Anterior Segment Optical Coherence Tomographv.AS-OCT)量化评价原发性闭角犁青光眼患者(Primary Angle Closure Glaucoma,PACG)早期干预后眼前段结构的改变.方法对确诊的早期PACG患者36例(60只眼)予以激光周边虹膜切开术(Laser Peripheral Iri-dotomy,LPI)进行早期干预;采用AS-OCT量化评价干预后眼前段结构的改变.对视力、眼压、房角开放情况及眼前段结构包括AOD500(巩膜突前500μm的房角开放距离)、前房轴深、晶状体厚度等进行观察,随访时间3个月.结果术后视力无明显变化,术后眼压较术前下降,差异有统计学意义(t=3.506,P<0.01).术后房角增宽,AOD500增加,差异有统计学意义(t=-8.34,P<0.01),术后前房轴深加深,差异有统计学意义,(t-2.909,P<0.01),术后晶状体厚度增加,差异有统计学意义(t-3.701,P<0.01 o结论AS-OCT的精确定量能够发现LPI术后眼前段结构的细微改变,是研究原发性闭角型青光眼早期于预的有力辅助工具.
목적 응용광학성상계통일전단OCT(Anterior Segment Optical Coherence Tomographv.AS-OCT)양화평개원발성폐각리청광안환자(Primary Angle Closure Glaucoma,PACG)조기간예후안전단결구적개변.방법 대학진적조기PACG환자36례(60지안)여이격광주변홍막절개술(Laser Peripheral Iri-dotomy,LPI)진행조기간예;채용AS-OCT양화평개간예후안전단결구적개변.대시력、안압、방각개방정황급안전단결구포괄AOD500(공막돌전500μm적방각개방거리)、전방축심、정상체후도등진행관찰,수방시간3개월.결과 술후시력무명현변화,술후안압교술전하강,차이유통계학의의(t=3.506,P<0.01).술후방각증관,AOD500증가,차이유통계학의의(t=-8.34,P<0.01),술후전방축심가심,차이유통계학의의,(t-2.909,P<0.01),술후정상체후도증가,차이유통계학의의(t-3.701,P<0.01 o결론AS-OCT적정학정량능구발현LPI술후안전단결구적세미개변,시연구원발성폐각형청광안조기우예적유력보조공구.
Objeetive To quantify the clinical features and the anatomical changes following laser pe-ripheral iridotomy(LPI)in early stage PACG with AS-OCT.Methods 36 early stage PACG patients(60 eyes) were evaluated using gonioscopy and AS-OCT.Anterior segment configuration including angle opening dis-tance at 500 micron anterior to the scleral spur, AOD500,anterior chamber depth,ACD,lens thickness, LT were determined.The following-up was 3 months.Results After LPI, visual acuity changed little after LPI, in-traocular pressure reduced(t =3.506, P <0.01 ), AODS00 became wider(t =-8.34, P <0.01 ), ACD deepened(t =-2.909,P <0.01 )and the lens became thicker(t =-3.701 ,P <0.01 ).Conclusions AS-OCT can make precise quantifying discriminations in the anterior segment changes in early stage PACG patients following LPI, AS-OCT can be a useful high quality instrument in PACG study.