CAJ | 학술논문

目的探讨血液透析(HD)患者并发肺动脉高压的发生率及肺动脉高压与心输出量的关系.方法运用超声心动图对78例HD患者并发肺动脉高压的发生率进行评估.以是否合并有肺动脉高压将研究对象分为肺动脉高压组和无肺动脉高压组,检测两组左心室射血分数、左心室容积、心输出量及心脏指数,并进行统计学分析.结果 78例HD患者并发肺动脉高压20例,发生率25.64%.20例并发肺动脉高压的患者中15例为轻度,4例为中度,1例为重度.两组间射血分数、心脏容积、心输出量及心脏指数差异均无统计学意义.心输出量与肺动脉高压无相关性.结论 HD患者并发肺动脉高压并不少见, 本研究中心输出量不是引起肺动脉压增高的原因.动-静脉内瘘及其他因素引起的心输出量的增加对肺动脉高压的影响有待进一步研究.
목적 탐토혈액투석(HD)환자병발폐동맥고압적발생솔급폐동맥고압여심수출량적관계.방법 운용초성심동도대78례HD환자병발폐동맥고압적발생솔진행평고.이시부합병유폐동맥고압장연구대상분위폐동맥고압조화무폐동맥고압조,검측량조좌심실사혈분수、좌심실용적、심수출량급심장지수,병진행통계학분석.결과 78례HD환자병발폐동맥고압20례,발생솔25.64%.20례병발폐동맥고압적환자중15례위경도,4례위중도,1례위중도.량조간사혈분수、심장용적、심수출량급심장지수차이균무통계학의의.심수출량여폐동맥고압무상관성.결론 HD환자병발폐동맥고압병불소견, 본연구중심수출량불시인기폐동맥압증고적원인.동-정맥내루급기타인소인기적심수출량적증가대폐동맥고압적영향유대진일보연구.
Objective To investigate the incidence and the relation between pulmonary hypertension (PH) and cardiac output in hemodialysis (HD) patients with PH. Methods The incidence of PH was estimated with Doppler echocardiography in 78 patients receiving HD. Left ventricular ejection fraction, cardiac volume, cardiac output and cardiac index were compared between patients with or without PH. Results PH was found in 20 patients (25.64%), among them15 had mild PH, 4 had moderate PH and 1 had severe PH. There was no statistical difference of ejection fraction, cardiac volume, cardiac output and cardiac index between the two groups. PH was not related to cardiac output. Conclusion HD can lead to PH, but cardiac output can not result in PH. Further investigations about the effect of elevated cardiac output induced by internal arteriovenous fistula and other factors on PH are needed.