国际皮肤性病学杂志
國際皮膚性病學雜誌
국제피부성병학잡지
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
2009年
3期
135-136
,共2页
蔡秀玲%仇宁%冯素英%李安生%冷欣彦%李小慧
蔡秀玲%仇寧%馮素英%李安生%冷訢彥%李小慧
채수령%구저%풍소영%리안생%랭흔언%리소혜
皮肤疾病%超敏反应%变应原%sIgE
皮膚疾病%超敏反應%變應原%sIgE
피부질병%초민반응%변응원%sIgE
Skin diseases%Hypersensitivity%Allergens%sIgE
目的 探讨南京地区变态反应性皮肤病患者血清中过敏原特异性IgE抗体水平.方法 采用免疫印迹法检测变态反应性皮肤病患者血清中过敏原特异性IgE抗体和总IgE抗体.结果 1 105例变态反应性皮肤病患者特异性IgE阳性率58.7%(649/1 105).检测的不同变态反应性皮肤病患者血清中过敏原特异件IgE抗体水平在吸入组中以屋尘过敏原特异性lgE抗体检出比例最高达36.83%(407/1105);其次是户尘螨,达23.26%(257/1105).在食物组中以腰果过敏原的检测比例最高,达7.33%(81/1105),其次是牛奶,达5.43%(60/1105).从性别上来看,男女在一些过敏原上差异有统计学意义.从年龄上来看,≤14岁组和＞14岁组在一些过敏原上,经统计分析差异有统计学意义.结论 特异性IgE抗体和总IgE检测可以帮助临床寻找相应的过敏原,为变态反应性皮肤病的预防和治疗提供参考.
目的 探討南京地區變態反應性皮膚病患者血清中過敏原特異性IgE抗體水平.方法 採用免疫印跡法檢測變態反應性皮膚病患者血清中過敏原特異性IgE抗體和總IgE抗體.結果 1 105例變態反應性皮膚病患者特異性IgE暘性率58.7%(649/1 105).檢測的不同變態反應性皮膚病患者血清中過敏原特異件IgE抗體水平在吸入組中以屋塵過敏原特異性lgE抗體檢齣比例最高達36.83%(407/1105);其次是戶塵螨,達23.26%(257/1105).在食物組中以腰果過敏原的檢測比例最高,達7.33%(81/1105),其次是牛奶,達5.43%(60/1105).從性彆上來看,男女在一些過敏原上差異有統計學意義.從年齡上來看,≤14歲組和＞14歲組在一些過敏原上,經統計分析差異有統計學意義.結論 特異性IgE抗體和總IgE檢測可以幫助臨床尋找相應的過敏原,為變態反應性皮膚病的預防和治療提供參攷.
목적 탐토남경지구변태반응성피부병환자혈청중과민원특이성IgE항체수평.방법 채용면역인적법검측변태반응성피부병환자혈청중과민원특이성IgE항체화총IgE항체.결과 1 105례변태반응성피부병환자특이성IgE양성솔58.7%(649/1 105).검측적불동변태반응성피부병환자혈청중과민원특이건IgE항체수평재흡입조중이옥진과민원특이성lgE항체검출비례최고체36.83%(407/1105);기차시호진만,체23.26%(257/1105).재식물조중이요과과민원적검측비례최고,체7.33%(81/1105),기차시우내,체5.43%(60/1105).종성별상래간,남녀재일사과민원상차이유통계학의의.종년령상래간,≤14세조화＞14세조재일사과민원상,경통계분석차이유통계학의의.결론 특이성IgE항체화총IgE검측가이방조림상심조상응적과민원,위변태반응성피부병적예방화치료제공삼고.
Objective To investigate the level of serum specific immunoglobulin E(sIgE) antibodies in patients with allergic dermatosis in Nanjing region.Methods A total of 1105 patients in Nanjing region with allergic dermatosis,including 625 cases of urticaria,293 cases of eczema,some cases of atopic dermatitis and other allergic dermatosis,were enrolled in this study.Immunoblotting test was used to detect serum slgE and toml IgE in these subjects.Results The prevalence of sIgE was 58.7%(649/1 105) in these patients.The most common inhalation allergen was housedust with a prevalence of 36.83% (407/1105),followed by house dust mites(23.26%,257/1105).Among food allergens,the highest positive rate belonged to cashew nut(7.33%,81/1105),and the second was milk(5.43%,60/1105).Moreover,significant difierence was observed in the frequency of sensitization to some allergens between female and male patients and between patients no older than 14 years and those older than 14 years (all P＜0.05).Conclusion Detection of serum sIgE and total IgE can help clinicians to find associated allergens.which may provide a basis for the prevention and treatment of common allergic dermatosis.
