中华健康管理学杂志
中華健康管理學雜誌
중화건강관이학잡지
CHINESE JOURNAL OF HEALTH MANAGEMENT
2012年
1期
32-35
,共4页
李晓鲁%戴红艳%何涛%尤淑玲%徐民%薛梅%周秀花%李涛%蔡卫东%闫素华%刘纪改%解建
李曉魯%戴紅豔%何濤%尤淑玲%徐民%薛梅%週秀花%李濤%蔡衛東%閆素華%劉紀改%解建
리효로%대홍염%하도%우숙령%서민%설매%주수화%리도%채위동%염소화%류기개%해건
高血压%运动%脑钠肽
高血壓%運動%腦鈉肽
고혈압%운동%뇌납태
Hypertension%Exercise%Brain natriuretic peptide
目的 探讨运动锻炼对高血压伴单纯左室舒张功能不全患者心功能及血脑钠肽的影响.方法 将66例高血压伴单纯左室舒张功能不全患者随机分为干预组和对照组.干预组在药物治疗基础上给予为期6个月的运动锻炼,对照组药物治疗同前,并保持平静生活方式.结果 通过6个月的运动锻炼,干预组与对照组比较:体重[(68 ±7)、(72±8)]kg；收缩压[(135.4±5.1)、(140.9±5.2)] mm Hg(1 mm Hg=0.133 kPa)、舒张压[(81.1±4.0)、(84.7 ±4.6)]mm Hg;纽约心脏学会分级(1.4±0.3)、(1.8±0.4)；N-端B型钠尿肽原[ (526±126)、(741±189)] ng/L明显下降；左室射血分数(62.9±6.7)、(59.O±5.6),E/A( 1.1±0.3)、(0.9±0.3)明显升高(均P＜0.05).结论 运动锻炼明显降低高血压伴单纯左室舒张功能不全患者血压、体重,同时改善心脏功能,是简单易行的健康教育项目.
目的 探討運動鍛煉對高血壓伴單純左室舒張功能不全患者心功能及血腦鈉肽的影響.方法 將66例高血壓伴單純左室舒張功能不全患者隨機分為榦預組和對照組.榦預組在藥物治療基礎上給予為期6箇月的運動鍛煉,對照組藥物治療同前,併保持平靜生活方式.結果 通過6箇月的運動鍛煉,榦預組與對照組比較:體重[(68 ±7)、(72±8)]kg；收縮壓[(135.4±5.1)、(140.9±5.2)] mm Hg(1 mm Hg=0.133 kPa)、舒張壓[(81.1±4.0)、(84.7 ±4.6)]mm Hg;紐約心髒學會分級(1.4±0.3)、(1.8±0.4)；N-耑B型鈉尿肽原[ (526±126)、(741±189)] ng/L明顯下降；左室射血分數(62.9±6.7)、(59.O±5.6),E/A( 1.1±0.3)、(0.9±0.3)明顯升高(均P＜0.05).結論 運動鍛煉明顯降低高血壓伴單純左室舒張功能不全患者血壓、體重,同時改善心髒功能,是簡單易行的健康教育項目.
목적 탐토운동단련대고혈압반단순좌실서장공능불전환자심공능급혈뇌납태적영향.방법 장66례고혈압반단순좌실서장공능불전환자수궤분위간예조화대조조.간예조재약물치료기출상급여위기6개월적운동단련,대조조약물치료동전,병보지평정생활방식.결과 통과6개월적운동단련,간예조여대조조비교:체중[(68 ±7)、(72±8)]kg；수축압[(135.4±5.1)、(140.9±5.2)] mm Hg(1 mm Hg=0.133 kPa)、서장압[(81.1±4.0)、(84.7 ±4.6)]mm Hg;뉴약심장학회분급(1.4±0.3)、(1.8±0.4)；N-단B형납뇨태원[ (526±126)、(741±189)] ng/L명현하강；좌실사혈분수(62.9±6.7)、(59.O±5.6),E/A( 1.1±0.3)、(0.9±0.3)명현승고(균P＜0.05).결론 운동단련명현강저고혈압반단순좌실서장공능불전환자혈압、체중,동시개선심장공능,시간단역행적건강교육항목.
Objective To investigate the effects of physical exercises on cardiac function and plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in hypertensive patients combined with diastolic cardiac dysfunction.Methods A total of 66 essential hypertension patients who had abnormal left ventricular relaxation and normal systolic function were assigned to the intervention group ( n =33 ; doing physical exercises once a day,5 days a week) or control group (n =33 ).All the patients received standard treatment.At 6 months,body weight,blood pressure,heart rate,NT-proBNP,and echocardiography were measured.Results At 6 months,body weight [ (68 ± 7 ) kg vs (72 ± 8 ) kg ],systolic blood pressure [ (135.4 ±5.1) mm Hg (1 mm Hg =0.133 kPa) vs (141.9 ±5.2) mm Hg ],diastolic blood pressure [ (81.1 ±4.0) mm Hg vs (84.7 ±4.6) mm Hg],New York Heart Association class (1.4 ±0.3 vs 1.8 ±0.4),NT-proBNP level [ (526 ± 126 ) ng/L vs (741 ± 189 ) ng/L] were significantly decreased in the intervention group when compared with the control group ( all P ＜ 0.05 ) although left ventricular ejection fraction (LVEF) (62.9 ±6.7 vs 59.0 ±5.6) and E/A ratio ( 1.1 ±0.3 vs 0.9 ±0.3) were significantly increased ( both P ＜ 0.05).Conclusion Physical exercises could play a role in reduced blood pressure and body weight and improved cardiac function in hypertensive patients with diastolic cardiac dysfunction.
