CAJ | 학술논문

目的联合使用两种生活质量问卷SF-36和QOL-35,评价冠心病患者经皮冠状动脉腔内成形术(PCI)后3个月生活质量变化,探讨PCI对冠心病患者生活质量的影响.方法连续观察2008年3月在北京协和医院心内科住院患者61例,按照是否行PCI将患者分为两组.使用SF-36和QOL-35对患者生活质量进行评估,3个月后随访患者并再次评测生活质量,采用多元协方差分析评估PCI对冠心病患者生活质量的影响.结果 24例非PCI组患者和37例PCI组患者性别(P=0.005)、心绞痛发作史(P=0.015)、吸烟史(P=0.037)和冠状动脉狭窄程度Judkins分级(P=0.001)的差异有统计学意义,其他临床基线资料的差异无统计学意义.用多元协方差分析控制基础水平的差异后,比较PCI对患者生活质量的影响,PCI对两组SF-36总分(P=0.044)、精神健康领域得分(P=0.003)、QOL-35总分(P=0.039)、社会功能领域得分(P=0.007)影响的差异有统计学意义.结论 PCI能提高冠心病患者的生活质量.
목적 연합사용량충생활질량문권SF-36화QOL-35,평개관심병환자경피관상동맥강내성형술(PCI)후3개월생활질량변화,탐토PCI대관심병환자생활질량적영향.방법 련속관찰2008년3월재북경협화의원심내과주원환자61례,안조시부행PCI장환자분위량조.사용SF-36화QOL-35대환자생활질량진행평고,3개월후수방환자병재차평측생활질량,채용다원협방차분석평고PCI대관심병환자생활질량적영향.결과 24례비PCI조환자화37례PCI조환자성별(P=0.005)、심교통발작사(P=0.015)、흡연사(P=0.037)화관상동맥협착정도Judkins분급(P=0.001)적차이유통계학의의,기타림상기선자료적차이무통계학의의.용다원협방차분석공제기출수평적차이후,비교PCI대환자생활질량적영향,PCI대량조SF-36총분(P=0.044)、정신건강영역득분(P=0.003)、QOL-35총분(P=0.039)、사회공능영역득분(P=0.007)영향적차이유통계학의의.결론 PCI능제고관심병환자적생활질량.
Objective To compare changes of quality of life at 3 months from baseline among patients who underwent and did not undergo percutaneous coronary intervention (PCI). Methods Sixty one patients with coronary artery disease, who were hospitalized in Cardiology Department in March 2008, were followed-up for 3 months after being discharged. SF-36 and QOL-35 were administered before PCI and at 3 months. Patients were divided into 2 groups according to whether they underwent PCI. Changes of quality of life scores between PCI and non-PCI groups were compared using analysis of covariance. Results There were 24 cases in non-PCI group and 37 in PCI group. Baseline characteristics were well balanced between PCI and non-PCI groups except gender (67.6% vs. 28.6% for male, P=0.005) , history of angina (56.8% vs. 23.8% , P=0.015) , smoking history(51.4% vs.23.8%,P=0.037) and Judkins classification of coronary artery(P=0.001). Multivariate analysis of covariance showed that the change of life quality between non-PCI group and PCI group in 3-months after discharge had statistical differences in total scores(P=0.044) and mental health scores (P=0.003) of SF-36, total scores (P=0.039) and social function scores (P=0.007) of QOL-35. Conclusion PCI can improve life quality in patients with coronary artery disease.