CAJ | 학술논문

目的观察二甲硅油散在胶囊内镜检查前对肠腔清洁度的影响及不良反应.方法 60例例接受胶囊内镜检查患者随机分为二甲硅油散组(常规服用聚乙二醇电解质散剂的基础上,检查前30 min口服二甲硅油散)和对照组(仅服用聚乙二醇电解质散剂),将每例胶囊所获得的小肠图像资料按照小肠通过时间平均分成A、B、C三段,由2位读片者分别根据肠腔内的气泡进行分级.并观察有无不良反应.结果 2位读片者间一致性较佳(P<0.05).在小肠的A段及C段中,二甲硅油散组较对照组有明显祛泡作用,大大提高的肠黏膜观察清晰度,差异有统计学意义(P<0.05).而在B段中,二甲硅油散组与对照组相比差异无统计学意义(P>0.05).结论胶囊内镜检查前服用二甲硅油散能提高小肠肠黏膜观察清晰度,无不良反应发生.
목적 관찰이갑규유산재효낭내경검사전대장강청길도적영향급불량반응.방법 60례례접수효낭내경검사환자수궤분위이갑규유산조(상규복용취을이순전해질산제적기출상,검사전30 min구복이갑규유산)화대조조(부복용취을이순전해질산제),장매례효낭소획득적소장도상자료안조소장통과시간평균분성A、B、C삼단,유2위독편자분별근거장강내적기포진행분급.병관찰유무불량반응.결과 2위독편자간일치성교가(P<0.05).재소장적A단급C단중,이갑규유산조교대조조유명현거포작용,대대제고적장점막관찰청석도,차이유통계학의의(P<0.05).이재B단중,이갑규유산조여대조조상비차이무통계학의의(P>0.05).결론 효낭내경검사전복용이갑규유산능제고소장장점막관찰청석도,무불량반응발생.
Objective To evaluate the effect of the dimethicone powder in bowel preparation before capsule endoscopy (CE) and to observe its possible adverse effects. Methods A total of 60 patients receiv-ing CE were prospectively randomized into 2 groups according to bowel preparation method. In dimethicone powder group, patients were arranged to take dimethicone powder 30 rain before the examination on basis of macrogol electrolytes powder and in control group, patients had macrogol electrolytes powder only. Images of small intestine were equally divided into segments A, B and C according to intestinal transit time, and re-viewed by 2 experienced physicians independently. Intraluminal gas bubbles were graded and any possible adverse effects were monitored. Results Interobserver agreement was excellent (P < 0.05). In segments A and C, images from dimethicone powder group were less interfered by gas bubble than those from control group (P < 0. 05), but in segment B there was no difference between 2 groups (P > O. 05). No adverse effects were observed. Conclusion The dimethicone powder administration before capsule endoscopy im-proves the visualization of the intestinal mucosa.