中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
8期
24-26
,共3页
苏寒锦%徐战平%丁勇泉%李汉强
囌寒錦%徐戰平%丁勇泉%李漢彊
소한금%서전평%정용천%리한강
膀胱肿瘤%尿道%电切术
膀胱腫瘤%尿道%電切術
방광종류%뇨도%전절술
Urinary bladder neoplasms%Urethra%Electrocision
目的 探讨经尿道二次电切术对浅表性膀胱癌术后复发的作用.方法 将120例经尿道等离子电切术治疗的浅表性膀胱癌患者采取机械抽样法随机分为两组,每组60例,试验组于首次电切术后4周进行二次电切术,外加丝裂霉素膀胱灌注化疗;对照组于首次电切术后加丝裂霉素膀胱灌注化疗.所有患者术后每3个月行膀胱镜复检,记录肿瘤复发的时间及数量、部位、大小等情况.结果 随访6～24(12.0±6.5)个月,试验组复发13例(21.7%,13/60),对照组复发38例(63.3%,38/60),试验组总体复发率较对照组明显降低(P＜0.01).试验组高级别肿瘤(G2～G3)复发率为26.2%(11/42),对照组为70.0%(35/50),试验组高级别肿瘤复发率较对照组明显降低(P＜0.01).结论 经尿道二次电切术可以降低浅表性膀胱癌(尤其是高级别肿瘤)的术后复发率,可以更准确地进行肿瘤分期和发现残存肿瘤,在临床治疗中有应用价值.
目的 探討經尿道二次電切術對淺錶性膀胱癌術後複髮的作用.方法 將120例經尿道等離子電切術治療的淺錶性膀胱癌患者採取機械抽樣法隨機分為兩組,每組60例,試驗組于首次電切術後4週進行二次電切術,外加絲裂黴素膀胱灌註化療;對照組于首次電切術後加絲裂黴素膀胱灌註化療.所有患者術後每3箇月行膀胱鏡複檢,記錄腫瘤複髮的時間及數量、部位、大小等情況.結果 隨訪6～24(12.0±6.5)箇月,試驗組複髮13例(21.7%,13/60),對照組複髮38例(63.3%,38/60),試驗組總體複髮率較對照組明顯降低(P＜0.01).試驗組高級彆腫瘤(G2～G3)複髮率為26.2%(11/42),對照組為70.0%(35/50),試驗組高級彆腫瘤複髮率較對照組明顯降低(P＜0.01).結論 經尿道二次電切術可以降低淺錶性膀胱癌(尤其是高級彆腫瘤)的術後複髮率,可以更準確地進行腫瘤分期和髮現殘存腫瘤,在臨床治療中有應用價值.
목적 탐토경뇨도이차전절술대천표성방광암술후복발적작용.방법 장120례경뇨도등리자전절술치료적천표성방광암환자채취궤계추양법수궤분위량조,매조60례,시험조우수차전절술후4주진행이차전절술,외가사렬매소방광관주화료;대조조우수차전절술후가사렬매소방광관주화료.소유환자술후매3개월행방광경복검,기록종류복발적시간급수량、부위、대소등정황.결과 수방6～24(12.0±6.5)개월,시험조복발13례(21.7%,13/60),대조조복발38례(63.3%,38/60),시험조총체복발솔교대조조명현강저(P＜0.01).시험조고급별종류(G2～G3)복발솔위26.2%(11/42),대조조위70.0%(35/50),시험조고급별종류복발솔교대조조명현강저(P＜0.01).결론 경뇨도이차전절술가이강저천표성방광암(우기시고급별종류)적술후복발솔,가이경준학지진행종류분기화발현잔존종류,재림상치료중유응용개치.
Objective To investigate the effect of repeat transurethral resection for superficial bladder cancer. Methods One hundred and twenty patients who were newly diagnosed superficial bladder cancer were divided randomly in to two groups by mechanical sampling method,60 patients underwent second of prostate TUPKVP 4 weeks after initial transurethral and received adjuvant MMC intravesically (experiment group) and the other 60 patients received adjuvant MMC following the initial TUPKVP(control group). The two groups were followed up by cystoscopy at 3-month intervals,and then compared the recurrences between the two groups. Carcinoma in situ or muscle invasive disease were excluded from the study. Results Mean following up time was 6-24 (12.0 ±6.5) months, within the following up period,recurrence was observed in 13 (21.7%, 13/60) patients in experiment group and in 38 (63.3%,38/60)patients in control group, there was signiticantly statistical difference between the two groups (P＜ 0.01). Of all the recurrences, the recurrence rate of high grade tumor was 26.2% (11/42) in experiment group and 70.0% (35/50) in control group,the recurrence rate in experiment group was obviously less than that in control group (P ＜ 0.01). Conclusions Repeat transurethral resection can lower the recurrence of superficial bladder cancer (especially for the high grade tumor) which with initial resection, it can improve the classification of malignant rumor, and find the residual tumor, so it has value in clinical treatment.
