CAJ | 학술논문

为研究首乌藤黄酮（flavonoids fromCaulis Polygoni Multiflori,简称FCPM）的体内抗氧化作用,将ICR小鼠自由分成四组,分别灌喂高、中、低剂量FCPM和生理盐水,30 d后眼眶采血及组织取样,用试剂盒测定小鼠血清、肝脏、脑组织中MDA含量、SOD和GSH-PX酶活性及血清、肝脏中CAT酶活性.结果表明,FCPM可显著降低血清及组织MDA含量,提高小鼠的血清及组织的SOD、GSH-PX和CAT活力,表明FCPM具有显著的体内抗氧化活性.
위연구수오등황동（flavonoids fromCaulis Polygoni Multiflori,간칭FCPM）적체내항양화작용,장ICR소서자유분성사조,분별관위고、중、저제량FCPM화생리염수,30 d후안광채혈급조직취양,용시제합측정소서혈청、간장、뇌조직중MDA함량、SOD화GSH-PX매활성급혈청、간장중CAT매활성.결과표명,FCPM가현저강저혈청급조직MDA함량,제고소서적혈청급조직적SOD、GSH-PX화CAT활력,표명FCPM구유현저적체내항양화활성.
To study the antioxidation effect in vivo of flavonoids from Caulis Polygoni Multiflori（FCPM）,ICR mices were randomly divided into 4 group（stomach irritation with high/middle/low FCPM and salineonly）,contents malondialdehyde（MDA）,enzyme activities of superoxide dismutase（SOD） and glutathione peroxidase（GSH-PX） in the serum,liver/brain and enzyme activities of Catalase（CAT） in the serum,liver of ICR mice were measured by reagent box.The results showed that FCPM can significantly increase the activity of SOD/GSH-PX in the serum,liver/brain and increase the activity of CAT in the serum/liver,decrease the contents of MDA in the serum and the organs.FCPM can improve antioxidation ability in vivo and balance the state of antioxidation/oxidation.