CAJ | 학술논문

合成了一种新型钴（Ⅲ）多吡啶类混配配合物[Co（phen）2dpapz]（ClO4）3.2H2O（phen=1,10-邻菲咯啉;dpapz=联吡啶并[3,2-a：2′,3′-c]6-氮杂-吩嗪）.通过元素分析、红外光谱、紫外光谱和循环伏安法对配合物进行了表征.应用电子吸收光谱、荧光光谱和粘度法研究了配合物与DNA的相互作用.结果表明,该配合物以插入方式与DNA结合,其键合常数为2.2×105L.mol-1.
합성료일충신형고（Ⅲ）다필정류혼배배합물[Co（phen）2dpapz]（ClO4）3.2H2O（phen=1,10-린비각람;dpapz=련필정병[3,2-a：2′,3′-c]6-담잡-분진）.통과원소분석、홍외광보、자외광보화순배복안법대배합물진행료표정.응용전자흡수광보、형광광보화점도법연구료배합물여DNA적상호작용.결과표명,해배합물이삽입방식여DNA결합,기건합상수위2.2×105L.mol-1.
A new Polypyridine cobalt（Ⅲ） mixed ligand complex of [Co（phen）2dpapz]（ClO4）3·2H2O（phen=1,10-phenanthroline,dppz=dipyrido[3,2-a：2′,3′-c]-6-azaphenazine） is synthesized and characterized by elemental analysis,IR,UV and electrochemical methods.The interaction of the complex [Co（phen）2dpapz]（ClO4）3·2H2O with DNA has been studied by absorption spectra,fluorescence spectra and viscosity measurements.The results suggest that the new polypyridine cobalt complex interacts with DNA by intercalative binding with a binding constant of 2.2×105L·mol-1.