天津医药
天津醫藥
천진의약
TIANJIN MEDICAL JOURNAL
2009年
12期
1020-1022
,共3页
糖尿病%2型%老年人%糖尿病并发症%心室功能%左%动脉硬化
糖尿病%2型%老年人%糖尿病併髮癥%心室功能%左%動脈硬化
당뇨병%2형%노년인%당뇨병병발증%심실공능%좌%동맥경화
diabetes mellitus%type 2 aged diabetes complications ventricular function%left arteriosclerosis
目的:探讨老年糖尿病患者左室质量变化与动脉僵硬度及其他影响因素之间的关系.方法:左室质量指数(LVMI)和脉搏波传导速度(PWV)分别作为评价左室质量(LVM)和动脉僵硬度的指标,对105例老年糖尿病患者的LVMI与PWV及其他影响因素之间进行Pearson分析及多元逐步回归分析.按LVMI值不同将患者分为无左室肥厚组与左室肥厚组,比较两组PWV值.结果:LVMI与PWV、收缩压、脉压、糖尿病病程及体质量指数(BMI)呈正相关(r值分别为 0.821、0.792、0.799、0.664、0.241, P ＜ 0.01 或 P ＜ 0.05).在相关基础上,选择相关性强的影响因素作自变量(X),以LVMI作应变量(Y),进行逐步回归分析,结果PWV(X_1)、收缩压(X_2)和糖尿病病程(X_3)进入回归分析.回归方程为=0.034X_1+0.779X_2+0.606X_3-21.706, F =146.741, R~2 =0.808.左室肥厚组的PWV明显高于无左室肥厚组的PWV(t = 9.109,P ＜ 0.01).结论:动脉僵硬度增加是导致老年糖尿病患者左室质量增加的重要因素之一.
目的:探討老年糖尿病患者左室質量變化與動脈僵硬度及其他影響因素之間的關繫.方法:左室質量指數(LVMI)和脈搏波傳導速度(PWV)分彆作為評價左室質量(LVM)和動脈僵硬度的指標,對105例老年糖尿病患者的LVMI與PWV及其他影響因素之間進行Pearson分析及多元逐步迴歸分析.按LVMI值不同將患者分為無左室肥厚組與左室肥厚組,比較兩組PWV值.結果:LVMI與PWV、收縮壓、脈壓、糖尿病病程及體質量指數(BMI)呈正相關(r值分彆為 0.821、0.792、0.799、0.664、0.241, P ＜ 0.01 或 P ＜ 0.05).在相關基礎上,選擇相關性彊的影響因素作自變量(X),以LVMI作應變量(Y),進行逐步迴歸分析,結果PWV(X_1)、收縮壓(X_2)和糖尿病病程(X_3)進入迴歸分析.迴歸方程為=0.034X_1+0.779X_2+0.606X_3-21.706, F =146.741, R~2 =0.808.左室肥厚組的PWV明顯高于無左室肥厚組的PWV(t = 9.109,P ＜ 0.01).結論:動脈僵硬度增加是導緻老年糖尿病患者左室質量增加的重要因素之一.
목적:탐토노년당뇨병환자좌실질량변화여동맥강경도급기타영향인소지간적관계.방법:좌실질량지수(LVMI)화맥박파전도속도(PWV)분별작위평개좌실질량(LVM)화동맥강경도적지표,대105례노년당뇨병환자적LVMI여PWV급기타영향인소지간진행Pearson분석급다원축보회귀분석.안LVMI치불동장환자분위무좌실비후조여좌실비후조,비교량조PWV치.결과:LVMI여PWV、수축압、맥압、당뇨병병정급체질량지수(BMI)정정상관(r치분별위 0.821、0.792、0.799、0.664、0.241, P ＜ 0.01 혹 P ＜ 0.05).재상관기출상,선택상관성강적영향인소작자변량(X),이LVMI작응변량(Y),진행축보회귀분석,결과PWV(X_1)、수축압(X_2)화당뇨병병정(X_3)진입회귀분석.회귀방정위=0.034X_1+0.779X_2+0.606X_3-21.706, F =146.741, R~2 =0.808.좌실비후조적PWV명현고우무좌실비후조적PWV(t = 9.109,P ＜ 0.01).결론:동맥강경도증가시도치노년당뇨병환자좌실질량증가적중요인소지일.
Objective: To evaluate the relationship between the change of left ventricular mass and arterial stiffness in the aged patients with diabetes mellitus. Methods: The pulse wave velocity (PWV) and left ventricular mass index(LVMI)were used to estimate the left ventricular mass and arterial stiffness. The relationship between LVMI and PWV and other influencing factors were evaluated with univariate analysis and stepwise regressive analysis in 105 patients with diabetes mellitus. The value of PWV was compared in the subjects of the left ventricular hypertrophy and the non- left ventricular hypertrophy groups. Results: LVMI was positively correlated with PWV, systolic blood pressure, pulse pressure,medical history and body mass index (the values of r were 0.821, 0.792, 0.799, 0.664 and 0.241 respectively,P ＜ 0.01 or P ＜ 0.05). A stepwise regression analysis was used to assess the combined influence of variables on left ventricular hypertrophy. The model included the following variables: PWV, systolic blood pressure and diabetes mellitus medical history. PWV value was significantly higher in patients with left ventricular hypertrophy than that of the patients without left ventricular hypertrophy(t = 9.109,P < 0.01). Conclusion: The increased arterial stiffness is one of the important factors which lead to the increased left ventricular mass index in aged patients with diabetes mellitus.
