国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
15期
2270-2272
,共3页
丙氨酸氨基转移酶(ALT)%献血%学生%初筛
丙氨痠氨基轉移酶(ALT)%獻血%學生%初篩
병안산안기전이매(ALT)%헌혈%학생%초사
Alanine aminotransferase%Blood donation%Students%Primary screening
目的 探讨在学校集体献血活动中,学生献血前血液初筛省略丙氨酸氨基转移酶(ALT)测定的可行性.方法 所有的献血者分为两大类:参加学校集体献血活动的学生献血者和除学生献血者外的其它献血者.ALT测定策略:其它献血者2007至2011年进行献血前初筛和采血后复检;学生献血者2007至2009年进行献血前初筛和采血后复检,而2010、2011年献血前省略初筛,仅采血后复检.结果判断:ALT>40 U/L为阳性.统计分析2007至2009年学生献血者与其它献血者初筛ALT的阳性率间的差异、学生献血者献血前初筛ALT的阳性率3年间的差异,2007至2011年学生献血者献血后复检ALT的阳性率5年间的差异.结果 2007至2009年,学生献血前ALT初筛的阳性率分别为:0.18%、0.20%、0.18%,其它献血者献血前ALT初筛的阳性率分别为:3.82%、4.00%、3.91%,两者献血前ALT初筛每年的阳性率间差异均有统计学意义(P<0.05);学生献血前ALT初筛的阳性率3年间差异无统计学意义(P>0.05).2007至2011年,学生献血后ALT复检的阳性率非常低,分别为:0.15%、0.12%、0.12%、0.20%、0.20%,5年间差异无统计学意义(P>0.05).结论 在学校集体献血活动中,学生献血者献血前初筛省略ALT测定对血液最终复检ALT的阳性率影响不大,与献血前初筛ALT的效果基本持平,献血前血液初筛可省略ALT的测定.
目的 探討在學校集體獻血活動中,學生獻血前血液初篩省略丙氨痠氨基轉移酶(ALT)測定的可行性.方法 所有的獻血者分為兩大類:參加學校集體獻血活動的學生獻血者和除學生獻血者外的其它獻血者.ALT測定策略:其它獻血者2007至2011年進行獻血前初篩和採血後複檢;學生獻血者2007至2009年進行獻血前初篩和採血後複檢,而2010、2011年獻血前省略初篩,僅採血後複檢.結果判斷:ALT>40 U/L為暘性.統計分析2007至2009年學生獻血者與其它獻血者初篩ALT的暘性率間的差異、學生獻血者獻血前初篩ALT的暘性率3年間的差異,2007至2011年學生獻血者獻血後複檢ALT的暘性率5年間的差異.結果 2007至2009年,學生獻血前ALT初篩的暘性率分彆為:0.18%、0.20%、0.18%,其它獻血者獻血前ALT初篩的暘性率分彆為:3.82%、4.00%、3.91%,兩者獻血前ALT初篩每年的暘性率間差異均有統計學意義(P<0.05);學生獻血前ALT初篩的暘性率3年間差異無統計學意義(P>0.05).2007至2011年,學生獻血後ALT複檢的暘性率非常低,分彆為:0.15%、0.12%、0.12%、0.20%、0.20%,5年間差異無統計學意義(P>0.05).結論 在學校集體獻血活動中,學生獻血者獻血前初篩省略ALT測定對血液最終複檢ALT的暘性率影響不大,與獻血前初篩ALT的效果基本持平,獻血前血液初篩可省略ALT的測定.
목적 탐토재학교집체헌혈활동중,학생헌혈전혈액초사성략병안산안기전이매(ALT)측정적가행성.방법 소유적헌혈자분위량대류:삼가학교집체헌혈활동적학생헌혈자화제학생헌혈자외적기타헌혈자.ALT측정책략:기타헌혈자2007지2011년진행헌혈전초사화채혈후복검;학생헌혈자2007지2009년진행헌혈전초사화채혈후복검,이2010、2011년헌혈전성략초사,부채혈후복검.결과판단:ALT>40 U/L위양성.통계분석2007지2009년학생헌혈자여기타헌혈자초사ALT적양성솔간적차이、학생헌혈자헌혈전초사ALT적양성솔3년간적차이,2007지2011년학생헌혈자헌혈후복검ALT적양성솔5년간적차이.결과 2007지2009년,학생헌혈전ALT초사적양성솔분별위:0.18%、0.20%、0.18%,기타헌혈자헌혈전ALT초사적양성솔분별위:3.82%、4.00%、3.91%,량자헌혈전ALT초사매년적양성솔간차이균유통계학의의(P<0.05);학생헌혈전ALT초사적양성솔3년간차이무통계학의의(P>0.05).2007지2011년,학생헌혈후ALT복검적양성솔비상저,분별위:0.15%、0.12%、0.12%、0.20%、0.20%,5년간차이무통계학의의(P>0.05).결론 재학교집체헌혈활동중,학생헌혈자헌혈전초사성략ALT측정대혈액최종복검ALT적양성솔영향불대,여헌혈전초사ALT적효과기본지평,헌혈전혈액초사가성략ALT적측정.
Objective To explore the feasibility of primary blood screening without ALT detection before blood donation in students.Methods All the blood donors were divided into two groups:student donors and other donors.Methods Primary ALT screening before blood donation and re-detection were performed from 2007 to 2011 in other donors and from 2007 to 2009 in student donors.And the student donors received only detection after donation but no primary screening in 2010 and 2011.ALT of > 40U/L was the positive result.The differences of positive rate of primary ALT screening between the student donors and other donors,the differences of positive rates in three years in student donors,and the differences of positive rate of re-detection of ALT in five years ( from 2007 to 2011 )were statistically analyzed.Results The positive rate of primary ALT screening was 0.18% in 2007,0.20% in 2008,and 0.18% in 2009 for student donors,and 3.82%,4.00%,and 3.91% for other donors,with a significant difference between the student and other donors in each year ( P< 0.05 ).There were no significant differences in the positive rate of ALT screening in student donors from 2007 to 2009 ( P> 0.05 ).The positive rate of re-detection of ALT in student donors from 2007 to 2011 was very low ( 0.15%,0.12%,0.12%,0.20%,and 0.20%,respectively ),with no significant difference among the five years.Conclusions In the activities of school collective donation,primary blood screening without ALT detection before blood donation in student donors has little effect on the final positive rate of ALT re-detection,basically equalling to the positive rate of primary screening,so ALT detected can be skipped in primary blood screening before donation.