CAJ | 학술논문

自体血清(血浆)因其富含广谱、齐全的基本营养成分和生物活性物质及对细胞生存、生长和生命活动具有调控或促进作用的细胞因子等,加上来源于自体的成分,因此,通常在应用上具备生物多样性、安全性、稳定性和相容性等特点和优势,使其在现代基础医学研究中的应用越来越广泛.为了进一步探究和更加科学地将自体血清(血浆)应用于体外细胞培养和组织工程研究中,本文通过对自体血清(血浆)的主要成分及基本生物学特性阐述自体血清(血浆)在细胞生物学和组织生物学研究中的应用.
자체혈청(혈장)인기부함엄보、제전적기본영양성분화생물활성물질급대세포생존、생장화생명활동구유조공혹촉진작용적세포인자등,가상래원우자체적성분,인차,통상재응용상구비생물다양성、안전성、은정성화상용성등특점화우세,사기재현대기출의학연구중적응용월래월엄범.위료진일보탐구화경가과학지장자체혈청(혈장)응용우체외세포배양화조직공정연구중,본문통과대자체혈청(혈장)적주요성분급기본생물학특성천술자체혈청(혈장)재세포생물학화조직생물학연구중적응용.
Rich in a broad spectrum of basic nutritional ingredients and bioactive substances and cytokines which regulated or promoted the cell viability, cell growth and vital movement, autologous serum (plasma) embraced the characteristics of biological diversity, security, stability, compatibility and so on. These advantages helped the increasingly wide application of autologous serum (plasma) in modem preclinical medicine studies. To further explore the scientific application of autologous serum (plasma) in cell culture and tissue engineering in vitro, this paper analyzed the main components and basic bionomics of autologous serum (plasma), and explained its application in cytobiology and histology within the field of preclinical medicine. Literature review suggested that autologous serum played an active role in normal or abnormal cell culture in vitro, cell proliferation and differentiation, cell morphology, structure and metabolism, as well as the in vitro tissue culture, self- renewal, and self-repair. Moreover, the diversity of its biological characteristics and security justifed the application of autologous serum (plasma) in preclinical medicine studies.