CAJ | 학술논문

为了比较慢性肝炎与其它疾病中肝阴虚证血浆血栓素B2(TXB2)和6-酮-前列腺素F1α6-Keto-PGF1α水平，用放射免疫法检测28例肝阴虚证患者血浆TXB2和6-Keto-PGF1α含量，又分慢性肝炎与其它疾病两组进行对比观测。结果表明，肝阴虚证患者血浆TXB2水平、T/6-K值显著高于健康对照组(均P＜0.01)，6-Keto-PGF1α水平显著低于健康对照组(P＜0.05)，慢性肝炎组与其它疾病组TXB2、T/6-K值均显著高于健康对照组(均P＜0.01)、6-Keto-PGF1α显著低于健康对照组(均P＜0.01)，且两组组间比较差异无显著性(P＞0.05)。提示肝阴虚证患者调节血管平滑肌舒缩功能的活性物质紊乱，存在微循环障碍。
위료비교만성간염여기타질병중간음허증혈장혈전소B2(TXB2)화6-동-전렬선소F1α6-Keto-PGF1α수평，용방사면역법검측28례간음허증환자혈장TXB2화6-Keto-PGF1α함량，우분만성간염여기타질병량조진행대비관측。결과표명，간음허증환자혈장TXB2수평、T/6-K치현저고우건강대조조(균P＜0.01)，6-Keto-PGF1α수평현저저우건강대조조(P＜0.05)，만성간염조여기타질병조TXB2、T/6-K치균현저고우건강대조조(균P＜0.01)、6-Keto-PGF1α현저저우건강대조조(균P＜0.01)，차량조조간비교차이무현저성(P＞0.05)。제시간음허증환자조절혈관평활기서축공능적활성물질문란，존재미순배장애。
The plasma thromboxane B2(TXB2) and 6-Keto-PGF1α(6-K) were determined by RIA in 28 patients with Liver Yin Deficiency (LYD).We compared the levels in 15 patients with chronic hepatitis (CH) and 13 patients with other diseases with the same syrdrome.The results showed that the levels of plasma TXB2、TXB2/6-K of patients with LYD were significantly higher than those of the normal group (P＜0.01)，and the levels of 6-Keto-PGF1α were lower than those of the normal group (P＜0.05). So did those of CH group and other diseases group (P＜0.01；P＜0.01).There is no significant difference between these two groups (P＞0.05) The results suggest that patients with LYD have dysfunction of the active substance regulating vascular smooth muscle and disturbance of microcirculation.