CAJ | 학술논문

目的：探讨椎体骨密度(BMD)与抗压强度的关系。方法：18具完整腰段脊柱标本(L1～L5)，用DEXA测试每个椎体的BMD，游离成单个椎体，按骨质疏松试行诊断标准分成正常对照组、轻中度骨质疏松组和重度骨质疏松组；测试椎体静态压缩下的最大抗压力和刚度。结果：正常对照组、轻中度骨质疏松组和重度骨质疏松组平均骨密度分别为(0.916±0.191)、 (0.594±0.116)和(0.402±0.096)g/cm2；三组间的最大抗压力分别为(7 037.2±1 525.9)、 (3 158.8±749.5)和(1 567.0±711.5)N；抗压刚度分别为(2 161.6±473.3)、 (1 085.5±265.2)和(608.6±315.2)N/mm。BMD与椎体最大抗压力和刚度呈正相关关系；三组间的BMD、最大抗压力和刚度均存在显著性差异(P＜0.01)。结论：椎体BMD与椎体的生物力学性质有明显的相关关系，是预测椎体压缩性骨折危险性的重要指标；老年人，尤其是绝经期妇女应检测BMD。
목적：탐토추체골밀도(BMD)여항압강도적관계。방법：18구완정요단척주표본(L1～L5)，용DEXA측시매개추체적BMD，유리성단개추체，안골질소송시행진단표준분성정상대조조、경중도골질소송조화중도골질소송조；측시추체정태압축하적최대항압력화강도。결과：정상대조조、경중도골질소송조화중도골질소송조평균골밀도분별위(0.916±0.191)、 (0.594±0.116)화(0.402±0.096)g/cm2；삼조간적최대항압력분별위(7 037.2±1 525.9)、 (3 158.8±749.5)화(1 567.0±711.5)N；항압강도분별위(2 161.6±473.3)、 (1 085.5±265.2)화(608.6±315.2)N/mm。BMD여추체최대항압력화강도정정상관관계；삼조간적BMD、최대항압력화강도균존재현저성차이(P＜0.01)。결론：추체BMD여추체적생물역학성질유명현적상관관계，시예측추체압축성골절위험성적중요지표；노년인，우기시절경기부녀응검측BMD。
Objective:To investigate the relationship between bone mineral density and vertebral compressive intensity.Methods:BMD of 18 cadaveric lumbar spines were evaluated with DEXA and be separated into individual vertebral bodies.According to their BMD,all vertebral bodies were divided into 3 groups:normal group(n=20);osteoporotic group(n=15) and serious osteoporotic group(n=15).The strengths and stiffness of those vertebral bodies were measured.Results:The average BMD is 0.916±0.191 g/cm2 in normal group;0.594±0.116 g/cm2 in osteoporotic group and 0.402±0.096 g/cm2 in serious osteoporotic group.The strength and stiffness were 7 037.2±1 525.9　N、2 161.6±473.3 N/mm in normal group;3 158.8±749.5　N,　1 085.5±265.2 N/mm in osteoporotic group and 1 567.0±711.5　N,　608.6±315.2 N/mm in serious osteoporotic group.Conclusion:It was suggested that the axial compression strength and stiffiness were influenced by BMD.It was necessary that the BMD should be measured for old people,especially for postmenopausal woman.