CAJ | 학술논문

为测定亚急性重症乙型肝炎患者血浆中纤维蛋白原的浓度与纤维蛋白单体聚合能力，以了解其凝血功能。用蕲蛇酶水解纤维蛋白原，用计算机测定其相关数值。发现20名亚急性重症乙型肝炎患者，其纤维蛋白聚合反应速率为(0.315±0.065) g/min；最大吸光度为(0.176±0.035) OD；纤维蛋白原浓度为 (150±30) mg/dl；纤维蛋白单体聚合反应速率/最大吸光度比值为1.789±0.160；反应延滞时间为(-21±5) s。结果表明：亚急性重症乙型肝炎患者的纤维蛋白原反应时间增快，但其它各项指标均下调，表明患者出血与凝血功能受损。
위측정아급성중증을형간염환자혈장중섬유단백원적농도여섬유단백단체취합능력，이료해기응혈공능。용기사매수해섬유단백원，용계산궤측정기상관수치。발현20명아급성중증을형간염환자，기섬유단백취합반응속솔위(0.315±0.065) g/min；최대흡광도위(0.176±0.035) OD；섬유단백원농도위 (150±30) mg/dl；섬유단백단체취합반응속솔/최대흡광도비치위1.789±0.160；반응연체시간위(-21±5) s。결과표명：아급성중증을형간염환자적섬유단백원반응시간증쾌，단기타각항지표균하조，표명환자출혈여응혈공능수손。
In order to detect plasma fibrinogen (Fbg) Level and fibrin monomer polymerize function in the patients with subacute serious hepatitis B, acutul-lase was used to hydrolyze fibrinagen and calculator automatic detection system used to measure the relative parameters. It was found that fibrin monomer polymerization reaction speed (FMPV) was 0.3150±0.065, maximum aftraction luminosity (Amax) 0.176±0.035, fibrinogen concentration(s) (150±30) mg/dl,　FMPV/Amax　1.789±0.160 and reaction delayed time (DT) -(21±5) s in 20 cases of subacute serious hepatitis B. The results showed that all the parameters were lower than normal except DT, suggesting the bleeding of the patients was related to the damage to coagulation function.