宁波大学学报(理工版)
寧波大學學報(理工版)
저파대학학보(리공판)
JOURNAL OF NINGBO UNIVERSITY (NSEE)
2000年
3期
121-124
,共4页
张咸宁%于冬雁%刘琼%陈念祖
張鹹寧%于鼕雁%劉瓊%陳唸祖
장함저%우동안%류경%진념조
结核分枝杆菌%DNA检测%基因组
結覈分枝桿菌%DNA檢測%基因組
결핵분지간균%DNA검측%기인조
Mycobacterium tuberculosis%DNA diagnosis%genome
全世界每年有300万死于结核病.DNA检测已成为结核分枝杆菌诊断的主要技术.1998年结核分枝杆菌H37Rv的全基因组序列被测定,并发现了候选毒型基因erp.这为人类认识结核分枝杆菌的致病分子机制和分子诊断开辟了前景.
全世界每年有300萬死于結覈病.DNA檢測已成為結覈分枝桿菌診斷的主要技術.1998年結覈分枝桿菌H37Rv的全基因組序列被測定,併髮現瞭候選毒型基因erp.這為人類認識結覈分枝桿菌的緻病分子機製和分子診斷開闢瞭前景.
전세계매년유300만사우결핵병.DNA검측이성위결핵분지간균진단적주요기술.1998년결핵분지간균H37Rv적전기인조서렬피측정,병발현료후선독형기인erp.저위인류인식결핵분지간균적치병분자궤제화분자진단개벽료전경.
Tuberculosis kills more than 3 million people per year worldwide. The DNA diagnosis ofMycobacterium tuberculosis is now the leading technology. The complete genome sequence of Mycobacteriumtuberculosis H37Rv has been published in 1998, and the erp gene may contribute to the virulence ofMycobacterium tuberculosis. These researches open the avenues for studying the pathogenetic mechanisms andmolecular diagnosis of the mycobacteria causing tuberculosis.