CAJ | 학술논문

目的：分析中枢神经系统(central nervous system，CNS)新型隐球菌感染临床特征。方法：对60例患者进行临床分析。结果：患者脑脊液呈无色浑浊、白细胞升高、其中以淋巴细胞和单核细胞为主。蛋白质升高、葡葡糖和氯化物减低，墨汁染色及苏木素-伊红染色均可发现新型隐球菌。几乎所有的患者有头痛、90％有发热、73％有呕吐、65％有不同程度的意识障碍和偏瘫、约半数还有听力减退、双目失明和抽搐。结论：脑脊液墨汁或苏木素-伊红染色检查有助于鉴别。
목적：분석중추신경계통(central nervous system，CNS)신형은구균감염림상특정。방법：대60례환자진행림상분석。결과：환자뇌척액정무색혼탁、백세포승고、기중이림파세포화단핵세포위주。단백질승고、포포당화록화물감저，묵즙염색급소목소-이홍염색균가발현신형은구균。궤호소유적환자유두통、90％유발열、73％유구토、65％유불동정도적의식장애화편탄、약반수환유은력감퇴、쌍목실명화추휵。결론：뇌척액묵즙혹소목소-이홍염색검사유조우감별。
Aim:To analyse the clinic manifestation of patients infected with cryptococcus neoformans in CNS. Methods: 60cases had been analysed and counted. Results: The CSF changes showed:no colour and turbidness, white blood cells wereraised,lymphocytes and mononuclears being prevailed ;protein increased ;glucose and chloride were declined. Cryptococcus neo-formans had been found with India-ink/hematoxylin-eosin staining. The clinic manifestations of patients were headache(nearly1 00 % ), fever (90%), vomiting (73%); consciousness disorder and hemiplegia (65%); hearing declined,losing the sight of botheyes and twitch (50%). Conclusion: The CSF India-ink/hematoxylin-eosin staining is critical to diagnose.