中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2009年
9期
1552-1553
,共2页
胰腺炎%高脂血症%综合分析
胰腺炎%高脂血癥%綜閤分析
이선염%고지혈증%종합분석
Pancreatitis%Hyperlipidemia%Meta-analysis
目的 了解高脂血症性急性胰腺炎(HL-AP)的临床特点,提高对HL-AP的认识.方法 回顾159例急性胰腺炎(AP)患者资料,其中18例HL-AP、141例为其他病因的AP,对两组的年龄、甘油三酯(TG)、血钙(Ca2+)、血糖(GLU)、CT严重指数(CTSI)、急性生理和慢性健康评分(APACHE Ⅱ)及合并糖尿病酮症酸中毒(DKA)的发生率进行比较,并将HL-AP组的TG值与上述指标进行相关分析.结果 HL-AP组与对照组相比除Ca2+明显下降外,TG、APACHE Ⅱ评分、CTSI、GLU和合并DKA的发生率均显著性增高(均P<0.05).HL-AP组TG值和APACHE Ⅱ评分、CTSI均呈正相关(均P<0.05);TG值和Ca2+水平存在直线负相关r=-0.795,P<0.01)关系.结论 HL-AP临床并不少见,其血清TG水平与HL-AP的病变程度呈正相关,且病情较严重,应重视对HL-AP的早期诊断和治疗.
目的 瞭解高脂血癥性急性胰腺炎(HL-AP)的臨床特點,提高對HL-AP的認識.方法 迴顧159例急性胰腺炎(AP)患者資料,其中18例HL-AP、141例為其他病因的AP,對兩組的年齡、甘油三酯(TG)、血鈣(Ca2+)、血糖(GLU)、CT嚴重指數(CTSI)、急性生理和慢性健康評分(APACHE Ⅱ)及閤併糖尿病酮癥痠中毒(DKA)的髮生率進行比較,併將HL-AP組的TG值與上述指標進行相關分析.結果 HL-AP組與對照組相比除Ca2+明顯下降外,TG、APACHE Ⅱ評分、CTSI、GLU和閤併DKA的髮生率均顯著性增高(均P<0.05).HL-AP組TG值和APACHE Ⅱ評分、CTSI均呈正相關(均P<0.05);TG值和Ca2+水平存在直線負相關r=-0.795,P<0.01)關繫.結論 HL-AP臨床併不少見,其血清TG水平與HL-AP的病變程度呈正相關,且病情較嚴重,應重視對HL-AP的早期診斷和治療.
목적 료해고지혈증성급성이선염(HL-AP)적림상특점,제고대HL-AP적인식.방법 회고159례급성이선염(AP)환자자료,기중18례HL-AP、141례위기타병인적AP,대량조적년령、감유삼지(TG)、혈개(Ca2+)、혈당(GLU)、CT엄중지수(CTSI)、급성생리화만성건강평분(APACHE Ⅱ)급합병당뇨병동증산중독(DKA)적발생솔진행비교,병장HL-AP조적TG치여상술지표진행상관분석.결과 HL-AP조여대조조상비제Ca2+명현하강외,TG、APACHE Ⅱ평분、CTSI、GLU화합병DKA적발생솔균현저성증고(균P<0.05).HL-AP조TG치화APACHE Ⅱ평분、CTSI균정정상관(균P<0.05);TG치화Ca2+수평존재직선부상관r=-0.795,P<0.01)관계.결론 HL-AP림상병불소견,기혈청TG수평여HL-AP적병변정도정정상관,차병정교엄중,응중시대HL-AP적조기진단화치료.
Objective To study the clinical features of hyperlipidemic acute pancreatitis(HL-AP)and to en-hyance the awareness of diagnosis and treatment of HL-AP. Methods To Retrospective analyse 159 cases with acute pancreatitis (AP), of which 18 cases of HL-AP(HL-AP group), 141 cases of other causes of AP(non-HL-AP group),to compare the age, triglyceride (TG), calcium (Ca2+) levels, blood glucose (GLU), CT severity index (CTSI), acute physiology and chronic health evaluation (APACHE Ⅱ) and the the incidence of combined diabetic ketoacidosis (DKA) in two groups,correlative analysis between TG in HL-AP group and the above-mentioned indicators was car-rird out. Results In addition to significantly decreased Ca22+ , TG, APACHEⅡ score, CTSI points, GLU, and the combined incidence of DKA were significantly increased (both P < 0. 05) in HL-AP group when compared with the control group,TG and APACHE Ⅱ score, CTSI score were positively correlated(P < 0. 05),TG and the Ca2+ was negatively correlated (r = - 0. 795, P < 0. 01). Conclusion HL-AP is not uncommon, mainly patients are young and middle-aged with positively correlated between serum TG levels and the HL-AP lesions, and the condition is more seri-ous and,we should pay attention to the early diagnosis and treatment of HL-AP, main treatment is non-surgical treat-ment.
