获得性免疫缺陷综合征%HIV%疾病传播,垂直%卫生服务
穫得性免疫缺陷綜閤徵%HIV%疾病傳播,垂直%衛生服務
획득성면역결함종합정%HIV%질병전파,수직%위생복무
Acquired immunodeficiency syndrome%HIV%Disease transmission,vertical%Health services
目的 了解我国预防HIV母婴传播(PMTCT)主要干预服务状况及其变化趋势.方法 收集2005年1月至2009年12月我国所有开展PMTCT工作地区的10 360 655名一般孕产妇接受常规孕产期保健和AIDS咨询检测服务状况的信息,并对其中确认HIV感染的10 123例孕产妇及其所产婴幼儿开展分阶段个案调查,收集包括应用抗病毒药物、安全分娩、人工喂养等PMTCT综合干预措施的相关信息,分析我国PMTCT主要干预措施落实情况及其变化趋势.结果 2005-2009年,我国孕产妇的AIDS咨询率呈逐年上升趋势(x2趋势=3184.5,P<0.001),2005年为69.8%(406 151/581 975),2006年为84.5%(1 346 745/1 594 579),2007年为90.3%(1 582 757/1 753 191),2008年为93.7%(1 926 224/2 055 232),2009年为82.3%(3 599 228/4 375 678);HIV抗体检测率呈逐年上升趋势(x2趋势=146 194.7,P<0.001),2005年为57.8%(336 459/581 975),2006年为80.8%(1 287 812/1 594 579),2007年为87.0%(1 524 595/1 753 191),2008年为89.2%(1 833 246/2 055 232),2009年为85.5%(3 741 337/4 375 678).10 123例HIV感染孕产妇中,有6156例分娩,HIV感染产妇抗病毒药物应用比例累计为71.0%(4373/6156),呈逐年上升趋势(x2趋势=47.6,P<0.001),2005年为64.6%(362/560),2006年为66.9%(623/931),2007年升至66.7%(857/1284),2008年为74.2%(977/1316),2009年为75.3%(1554/2065);孕期用药比例为58.5%(2557/4373).HIV感染产妇所产婴幼儿的抗病毒药物应用比例为83.4%(4999/5994),呈逐年上升趋势(x2趋势=13.0,P<0.001),2005年为77.2%(409/530),2006年为80.1%(720/899),2007年为83.8%(1053/1257),2008年为89.4%(1116/1249),2009年为82.6%(1701/2059);人工喂养比例为92.9%(5276/5681),18月龄HIV抗体检测比例为74.6%(2482/3324).结论 一般孕产妇人群咨询率与HIV检测率逐年提高,但孕期检测比例较低;各项PMTCT主要干预措施落实比例逐年提高.
目的 瞭解我國預防HIV母嬰傳播(PMTCT)主要榦預服務狀況及其變化趨勢.方法 收集2005年1月至2009年12月我國所有開展PMTCT工作地區的10 360 655名一般孕產婦接受常規孕產期保健和AIDS咨詢檢測服務狀況的信息,併對其中確認HIV感染的10 123例孕產婦及其所產嬰幼兒開展分階段箇案調查,收集包括應用抗病毒藥物、安全分娩、人工餵養等PMTCT綜閤榦預措施的相關信息,分析我國PMTCT主要榦預措施落實情況及其變化趨勢.結果 2005-2009年,我國孕產婦的AIDS咨詢率呈逐年上升趨勢(x2趨勢=3184.5,P<0.001),2005年為69.8%(406 151/581 975),2006年為84.5%(1 346 745/1 594 579),2007年為90.3%(1 582 757/1 753 191),2008年為93.7%(1 926 224/2 055 232),2009年為82.3%(3 599 228/4 375 678);HIV抗體檢測率呈逐年上升趨勢(x2趨勢=146 194.7,P<0.001),2005年為57.8%(336 459/581 975),2006年為80.8%(1 287 812/1 594 579),2007年為87.0%(1 524 595/1 753 191),2008年為89.2%(1 833 246/2 055 232),2009年為85.5%(3 741 337/4 375 678).10 123例HIV感染孕產婦中,有6156例分娩,HIV感染產婦抗病毒藥物應用比例纍計為71.0%(4373/6156),呈逐年上升趨勢(x2趨勢=47.6,P<0.001),2005年為64.6%(362/560),2006年為66.9%(623/931),2007年升至66.7%(857/1284),2008年為74.2%(977/1316),2009年為75.3%(1554/2065);孕期用藥比例為58.5%(2557/4373).HIV感染產婦所產嬰幼兒的抗病毒藥物應用比例為83.4%(4999/5994),呈逐年上升趨勢(x2趨勢=13.0,P<0.001),2005年為77.2%(409/530),2006年為80.1%(720/899),2007年為83.8%(1053/1257),2008年為89.4%(1116/1249),2009年為82.6%(1701/2059);人工餵養比例為92.9%(5276/5681),18月齡HIV抗體檢測比例為74.6%(2482/3324).結論 一般孕產婦人群咨詢率與HIV檢測率逐年提高,但孕期檢測比例較低;各項PMTCT主要榦預措施落實比例逐年提高.
목적 료해아국예방HIV모영전파(PMTCT)주요간예복무상황급기변화추세.방법 수집2005년1월지2009년12월아국소유개전PMTCT공작지구적10 360 655명일반잉산부접수상규잉산기보건화AIDS자순검측복무상황적신식,병대기중학인HIV감염적10 123례잉산부급기소산영유인개전분계단개안조사,수집포괄응용항병독약물、안전분면、인공위양등PMTCT종합간예조시적상관신식,분석아국PMTCT주요간예조시락실정황급기변화추세.결과 2005-2009년,아국잉산부적AIDS자순솔정축년상승추세(x2추세=3184.5,P<0.001),2005년위69.8%(406 151/581 975),2006년위84.5%(1 346 745/1 594 579),2007년위90.3%(1 582 757/1 753 191),2008년위93.7%(1 926 224/2 055 232),2009년위82.3%(3 599 228/4 375 678);HIV항체검측솔정축년상승추세(x2추세=146 194.7,P<0.001),2005년위57.8%(336 459/581 975),2006년위80.8%(1 287 812/1 594 579),2007년위87.0%(1 524 595/1 753 191),2008년위89.2%(1 833 246/2 055 232),2009년위85.5%(3 741 337/4 375 678).10 123례HIV감염잉산부중,유6156례분면,HIV감염산부항병독약물응용비례루계위71.0%(4373/6156),정축년상승추세(x2추세=47.6,P<0.001),2005년위64.6%(362/560),2006년위66.9%(623/931),2007년승지66.7%(857/1284),2008년위74.2%(977/1316),2009년위75.3%(1554/2065);잉기용약비례위58.5%(2557/4373).HIV감염산부소산영유인적항병독약물응용비례위83.4%(4999/5994),정축년상승추세(x2추세=13.0,P<0.001),2005년위77.2%(409/530),2006년위80.1%(720/899),2007년위83.8%(1053/1257),2008년위89.4%(1116/1249),2009년위82.6%(1701/2059);인공위양비례위92.9%(5276/5681),18월령HIV항체검측비례위74.6%(2482/3324).결론 일반잉산부인군자순솔여HIV검측솔축년제고,단잉기검측비례교저;각항PMTCT주요간예조시락실비례축년제고.
Objective The purpose of this study is to get to know the intervention services implementation status of prevention of mother to child transmission (PMTCT) of HIV/AIDS in China,and the trend of recent five years. Methods We carried out relevant surveys and investigations among the areas where PMTCT work had been implemented during January 2005 to December 2009. Health providers in these fields provided routine maternal health care, HIV counseling and test for 10 360 655 pregnant women and comprehensive intervention measures to 10 123 HIV infected pregnant women which included antiretroviral (ARV) drugs usage,safety delivery,and exclusive breastfeeding,and collected relevant data and materials to analysis the ratio of main interventions and its change trend. Results The HIV/AIDS counseling rate was increasing year by year (x2trend= 3184. 5, P< 0.001 ), during 2005 to 2009 the rate was 69. 8% (406 151/581 975), 84.5% (1 346 745/1 594 579), 90.3% ( 1 582 757/1 753 191 ), 93.7% (1 926 224/2 055 232),82. 3% (3 599 228/4 375 678) respectively. HIV/AIDS test rate was increasing (x2trend = 146 194. 7, P < 0. 001 ), the rate from 2005 to 2009 was 57. 8% ( 336 459/581 975 ), 80. 8% ( 1 287 812/1 594 579 ), 87. 0% ( 1 524 595/1 753 191 ), 89. 2% ( 1 833 246/2 055 232 ), 85.5% (3 741 337/4 375 678)respectively. The total number of HIV/AIDS infected maternities was 10 123 during 2005- 2009, 6156 of them delivered, the general usage rate of ARVs was 71.0% (4373/6156), and increasing to 75.3% ( 1554/2065 ) by the end of 2009, the rates of 2005 to 2008 were 64. 6% ( 362/560 ),66. 9% (623/931), 66. 7% ( 857/1284 ), 74. 2% ( 977/1316 ) respectively. The difference was significant ( xtrend = 47.6, P < 0. 001 ). The proportion of using ARVs during pregnant period was 58.5% (2557/4373).The proportion of using ARVs among born infants of HIV infected maternities was 83.4% (4999/5994) ,and increasing yearly,77.2% ( 409/530 ) of 2005,80. 1% ( 720/899 ) of 2006,83. 8% ( 1053/1257 ) of 2007,89.4%(1116/1249)of2008,82.6%(1701/2059)of2009,the difference wassignificant (x trend =13.0,P<0. 001 ). The general rate of exclusive breastfeeding was 92. 9% (5276/5681) and the rate of HIV test in 18 months was 74. 6% (2482/3324). Conclusion The rate of HIV/AIDS counseling and test of general maternities is increasing and the proportion of mainly intervention me asures have been increased year by year.