CAJ | 학술논문

目的探讨咽异感症患者焦虑和抑郁症状的治疗效果.方法用汉密顿焦虑量表(HAMA)和抑郁量表(HAMD)前瞻性评估109例咽异感症患者,分为对照组(30例)和观察组(79例).对照组采用常规治疗,观察组在常规疗法的基础上,给予抗焦虑和抑郁治疗即盐酸帕罗西汀、苯二氮卓类药物治疗.结果治疗8周后随访,对照组有效率为50.0%(15/30),观察组为87.3%(69/79),统计学分析表明2组之间差异有显著性(P<0.005).观察组抗焦虑和抑郁治疗后HAMA和HAMD积分较治疗前明显减少(P<0.01).结论焦虑和抑郁症状在咽异感症患者中极为常见,抗焦虑抑郁治疗效果确切,可以作为咽异感症的治疗选择.
목적 탐토인이감증환자초필화억욱증상적치료효과.방법 용한밀돈초필량표(HAMA)화억욱량표(HAMD)전첨성평고109례인이감증환자,분위대조조(30례)화관찰조(79례).대조조채용상규치료,관찰조재상규요법적기출상,급여항초필화억욱치료즉염산파라서정、분이담탁류약물치료.결과 치료8주후수방,대조조유효솔위50.0%(15/30),관찰조위87.3%(69/79),통계학분석표명2조지간차이유현저성(P<0.005).관찰조항초필화억욱치료후HAMA화HAMD적분교치료전명현감소(P<0.01).결론 초필화억욱증상재인이감증환자중겁위상견,항초필억욱치료효과학절,가이작위인이감증적치료선택.
Objective To investigate therapeutic effect of anxious and depressive disorders in patients with globus pharyngeus.Methods 109 patients with globus pharyngeus were assessed prospectively with Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD),and were divided into control group(30) and observed group(79).The routine method was employed to the control group patients.Antianxiety agents and antidepressants such as paroxetine hydrochloride,benzodiazepines were added to the observed group patients.Results 15(50.0%) patients recovered in the control group,and 69(87.3%) in the observed group after 8 weeks treatment.Statistical analysis showed that there were significant difference of therapeutic effects between 2 groups(P<0.005).The scores of HAMA and HAMD in the observed group after treatment of antianxiety agents and antidepressants were much less than that before treatment (P<0.01).Conclusion There is a high prevalence of anxious and depressive disorders in patients with globus pharyngeus to be found at present study.The treatments of globus pharyngeus with antianxiety agents and antidepressants are apparent effective in the study,and may be considered as one of the alternative methods.