CAJ | 학술논문

Wolbachia是一类广泛共生于节肢动物和线虫体内的立克次体,能够通过细胞质不亲和、孤雌生殖、雄性雌性化和杀雄等多种机制调控节肢动物的生殖行为,并在丝虫发育、生殖和致病过程中发挥重要作用.近年来的研究结果显示Wolbachia在水平基因转移、抗病毒作用、物种进化等方面亦具有重要价值.该文对Wolbachia近年研究成果进行综述,重点介绍其生物学特征、传播方式、对共生宿主的影响作用及其意义,初步探讨了其在媒介生物防治与相关疾病控制中的潜在价值.
Wolbachia시일류엄범공생우절지동물화선충체내적립극차체,능구통과세포질불친화、고자생식、웅성자성화화살웅등다충궤제조공절지동물적생식행위,병재사충발육、생식화치병과정중발휘중요작용.근년래적연구결과현시Wolbachia재수평기인전이、항병독작용、물충진화등방면역구유중요개치.해문대Wolbachia근년연구성과진행종술,중점개소기생물학특정、전파방식、대공생숙주적영향작용급기의의,초보탐토료기재매개생물방치여상관질병공제중적잠재개치.
Intracellular rickettsial bacteria of the genus Wolbachia are found in numerous invertebrates including insects and nematodes. In their insect hosts, Wolbachia often manipulate the reproductive mode of their hosts, causing cytoplasmic incompatibility(CI), parthenogenesis induction(PI), feminization of genetic,or male killing(MK). Many studies have determined that filarial pathogenesis were reliant on this endosymbiont for embryogenesis, growth and survival. Additional researches have also focused on determining the role of Wolbachia in horizontal gene transfer, antiviral responses, potential applications in pest and disease vector control,speciation and so on. This review summarized the significant advances in the study of Wolbachia. Future research directions of this interesting intracellular rickettsial bacteria are also discussed.