国际免疫学杂志
國際免疫學雜誌
국제면역학잡지
INTERNATIONAL JOURNAL OF IMMUNOLOGY
2010年
2期
92-96
,共5页
肿瘤坏死因子样弱凋亡诱导因子%自身免疫性疾病%成纤维细胞生长因子诱导因子14
腫瘤壞死因子樣弱凋亡誘導因子%自身免疫性疾病%成纖維細胞生長因子誘導因子14
종류배사인자양약조망유도인자%자신면역성질병%성섬유세포생장인자유도인자14
TNF-like weak inducer of apoptosis%Autoimmune disease%Fn14
肿瘤坏死因子样弱凋亡诱导因子(TWEAK)是肿瘤坏死因子配体超家族的新成员,按被发现的时间先后称为第十二成员(TNPSF12),现发现其具有广泛的生物学活性,在多个系统的疾病发病机制中起着重要作用.
腫瘤壞死因子樣弱凋亡誘導因子(TWEAK)是腫瘤壞死因子配體超傢族的新成員,按被髮現的時間先後稱為第十二成員(TNPSF12),現髮現其具有廣汎的生物學活性,在多箇繫統的疾病髮病機製中起著重要作用.
종류배사인자양약조망유도인자(TWEAK)시종류배사인자배체초가족적신성원,안피발현적시간선후칭위제십이성원(TNPSF12),현발현기구유엄범적생물학활성,재다개계통적질병발병궤제중기착중요작용.
TWEAK(TNF-like weak inducer of apoptosis),is a novel member of the TNF supeffamilies,also known as TNFSF12(TNF-superfamily member 12).TWEAK is a multifunctional cytokine which has extrensive biological activities,plays a important role in pathogenesis of many diseases,especially in autoimmune diseases.In this review,we summaries the advance of TWEAK in autoimmune diseases.
