中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2009年
3期
437-438
,共2页
周序玲%隆琰%林春招%江远仕%陆学东%杨衬%黄烈%曹火太%陈小可%李梅
週序玲%隆琰%林春招%江遠仕%陸學東%楊襯%黃烈%曹火太%陳小可%李梅
주서령%륭염%림춘초%강원사%륙학동%양츤%황렬%조화태%진소가%리매
鼻炎%微生物%分布%呼吸道感染
鼻炎%微生物%分佈%呼吸道感染
비염%미생물%분포%호흡도감염
Rhinitis%Germ%Distribution%Respiratory tract infection
目的 探讨急性鼻炎患者鼻腔微生物的分布特点及与呼吸道感染的相关性.方法 436例急性鼻炎患者,根据是否伴有呼吸道感染而随机分为感染组(314例)和非感染组(122例).取鼻液进行鼻腔微生物检测,同时检测血清白细胞介素4(IL-4)和干扰素γ(IFN-γ)含量.结果 感染组和非感染组中鼻腔细菌的分布以金黄色葡萄球菌最多(分别占58.6%和31.2%),其次是表皮葡萄球菌(分别占44.9%和46.7%)、肺炎杆菌(分别占7.9%和4.9%)、大肠杆菌(分别占3.5%和1.6%);真菌主要为不解糖消化链球菌(分别占1.9%和1.6%)、迟缓真杆菌(分别占1.6%和0)和黏液真杆菌(分别占0.9%和0.8%);病毒主要为合胞病毒、鼻病毒、腺病毒、流感病毒、副流感病毒和冠状病毒.伴有呼吸道感染的患者血清IL-4含量比非感染组显著增高(P＜0.05),而IFN-γ含量显著降低(P＜0.05)结论金黄色葡萄球菌、合胞病毒、鼻病毒、腺病毒、流感病毒与呼吸道的感染有密切的关系,可引起机体的免疫功能紊乱.
目的 探討急性鼻炎患者鼻腔微生物的分佈特點及與呼吸道感染的相關性.方法 436例急性鼻炎患者,根據是否伴有呼吸道感染而隨機分為感染組(314例)和非感染組(122例).取鼻液進行鼻腔微生物檢測,同時檢測血清白細胞介素4(IL-4)和榦擾素γ(IFN-γ)含量.結果 感染組和非感染組中鼻腔細菌的分佈以金黃色葡萄毬菌最多(分彆佔58.6%和31.2%),其次是錶皮葡萄毬菌(分彆佔44.9%和46.7%)、肺炎桿菌(分彆佔7.9%和4.9%)、大腸桿菌(分彆佔3.5%和1.6%);真菌主要為不解糖消化鏈毬菌(分彆佔1.9%和1.6%)、遲緩真桿菌(分彆佔1.6%和0)和黏液真桿菌(分彆佔0.9%和0.8%);病毒主要為閤胞病毒、鼻病毒、腺病毒、流感病毒、副流感病毒和冠狀病毒.伴有呼吸道感染的患者血清IL-4含量比非感染組顯著增高(P＜0.05),而IFN-γ含量顯著降低(P＜0.05)結論金黃色葡萄毬菌、閤胞病毒、鼻病毒、腺病毒、流感病毒與呼吸道的感染有密切的關繫,可引起機體的免疫功能紊亂.
목적 탐토급성비염환자비강미생물적분포특점급여호흡도감염적상관성.방법 436례급성비염환자,근거시부반유호흡도감염이수궤분위감염조(314례)화비감염조(122례).취비액진행비강미생물검측,동시검측혈청백세포개소4(IL-4)화간우소γ(IFN-γ)함량.결과 감염조화비감염조중비강세균적분포이금황색포도구균최다(분별점58.6%화31.2%),기차시표피포도구균(분별점44.9%화46.7%)、폐염간균(분별점7.9%화4.9%)、대장간균(분별점3.5%화1.6%);진균주요위불해당소화련구균(분별점1.9%화1.6%)、지완진간균(분별점1.6%화0)화점액진간균(분별점0.9%화0.8%);병독주요위합포병독、비병독、선병독、류감병독、부류감병독화관상병독.반유호흡도감염적환자혈청IL-4함량비비감염조현저증고(P＜0.05),이IFN-γ함량현저강저(P＜0.05)결론금황색포도구균、합포병독、비병독、선병독、류감병독여호흡도적감염유밀절적관계,가인기궤체적면역공능문란.
Objective To explore microbic distribution feature of acute rhinitis pafienta' nasal cavity and dependabihty research of respiratory infection.Methods 436 acute rhinitis pafienta were randomly divided tO infection group(314)and non-infection group(122)depended on whether accompanying respiratory infection.Take blenna narium and carry out nasal cavity microbiological detection,meanwhile take blood and mesasure the content of serum IL-4 and IFN-γ.Results The staphylococcus aureus taked the most proportion(58.6%and 3 1.2%)of nasal cavity bacterial distribution in infection group and non-infection group,the following bacterium were the staphylococcus epidermidis(44.9%and 46.7%),bacillus meningitidis purulentae(7.9%and 4.9%)and bacillus coli(3.5%and 1.6%),the major eumycete were the peptostreptococcus asaeeharolyticus(1.9%and 1.6%),eubacterium lentum (1.6%and 0)and eubacterium mucus(0.9%and 0.8%),the major virus were the syncytial virus,the rhinoviru8es,adenodrus,influenza virus,parainfluenze virus and coronaviruses.The respiratory tract infection patients' content of serum IL-4 Were significant higher(P＜0.05)than the non-infection group,but the content ofIFN-γ were signifieanfly reduced(P＜0.05).Conclusion The staphylococcus aureus,syncytial virus,rhinoviruses,adenovirus and influenza virus have the close relation with the infection of the respiratory tract,which can cause the disorder of organism immune function.
