中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2010年
11期
1183-1185
,共3页
腹膜透析%C反应蛋白%低白蛋白血症%炎症
腹膜透析%C反應蛋白%低白蛋白血癥%炎癥
복막투석%C반응단백%저백단백혈증%염증
Peritoneal dialysis%C-reactive protein%Hypoproteinemia%Inflammation
目的 研究腹膜透析患者并发低蛋白血症的发生情况,探讨其与C-反应蛋白(CRP)及其与各种炎性并发症的关系.方法 对2006年1月至2009年6月入院的60例持续性不卧床腹膜透析(CAPD)患者进行血清白蛋白(ALB)含量及其引发的相关并发症进行调查.根据ALB含量分为A组和B组,其中A组为营养良好,ALB含量正常;B组为合并低白蛋白血症患者.比较2组间CRP、转铁蛋白(TF)和主观营养评估法(SGA)的变化及其与临床并发症的关系.采用t检验及Pearson相关分析.结果 60例CAPD患者中,B组患者CRP含量[(8.40±1.32)mg/L]显著高于A组[(2.14±0.87)mg/L](P＜0.01);B组腹膜炎发生率为6.7%,肺炎发生率为13.3%,心血管疾病的发生率为16.7%,均明显高于A组(腹膜炎发生率为0,肺炎发生率为10%,心血管疾病的发生率为6.7%)(P均＜0.05).结论 CAPD合并低白蛋白血症患者并发炎症及心血管疾病的发生率皆高于营养良好者.应重视腹膜透析患者营养不良-炎症-心血管疾病(动脉粥样硬化)综合征的诊治.
目的 研究腹膜透析患者併髮低蛋白血癥的髮生情況,探討其與C-反應蛋白(CRP)及其與各種炎性併髮癥的關繫.方法 對2006年1月至2009年6月入院的60例持續性不臥床腹膜透析(CAPD)患者進行血清白蛋白(ALB)含量及其引髮的相關併髮癥進行調查.根據ALB含量分為A組和B組,其中A組為營養良好,ALB含量正常;B組為閤併低白蛋白血癥患者.比較2組間CRP、轉鐵蛋白(TF)和主觀營養評估法(SGA)的變化及其與臨床併髮癥的關繫.採用t檢驗及Pearson相關分析.結果 60例CAPD患者中,B組患者CRP含量[(8.40±1.32)mg/L]顯著高于A組[(2.14±0.87)mg/L](P＜0.01);B組腹膜炎髮生率為6.7%,肺炎髮生率為13.3%,心血管疾病的髮生率為16.7%,均明顯高于A組(腹膜炎髮生率為0,肺炎髮生率為10%,心血管疾病的髮生率為6.7%)(P均＜0.05).結論 CAPD閤併低白蛋白血癥患者併髮炎癥及心血管疾病的髮生率皆高于營養良好者.應重視腹膜透析患者營養不良-炎癥-心血管疾病(動脈粥樣硬化)綜閤徵的診治.
목적 연구복막투석환자병발저단백혈증적발생정황,탐토기여C-반응단백(CRP)급기여각충염성병발증적관계.방법 대2006년1월지2009년6월입원적60례지속성불와상복막투석(CAPD)환자진행혈청백단백(ALB)함량급기인발적상관병발증진행조사.근거ALB함량분위A조화B조,기중A조위영양량호,ALB함량정상;B조위합병저백단백혈증환자.비교2조간CRP、전철단백(TF)화주관영양평고법(SGA)적변화급기여림상병발증적관계.채용t검험급Pearson상관분석.결과 60례CAPD환자중,B조환자CRP함량[(8.40±1.32)mg/L]현저고우A조[(2.14±0.87)mg/L](P＜0.01);B조복막염발생솔위6.7%,폐염발생솔위13.3%,심혈관질병적발생솔위16.7%,균명현고우A조(복막염발생솔위0,폐염발생솔위10%,심혈관질병적발생솔위6.7%)(P균＜0.05).결론 CAPD합병저백단백혈증환자병발염증급심혈관질병적발생솔개고우영양량호자.응중시복막투석환자영양불량-염증-심혈관질병(동맥죽양경화)종합정적진치.
Objective To test the serum albumin level in patients having the peritoneal dialysis,and investigate its relationship with C-reactive protein(CRP)level or other inflammatory complications. Methods Sixty patients having peritoneal dialysis treatment were divided into two groups based on the serum albumin(ALB)level,patients had normal ALB level were included into group A,while the patients with serum hypoproteinemia were included into group B. The serum level of CRP,transferin(TF)and nutritional status were compared between two groups,and their relationship with clinical complications were evaluated. Results The serum CRP level in patients of group B(8.40 ± 1.32)mg/L was significantly higher than group A(2. 14 ±0.87)mg/L(P ＜0. 01). Patients from group B had more inflammation complications,such as peritonitis(6. 7%),pneumonia(13. 3%),cardiovascular disease(16.7%). Conclusions The continuous ambulatory peritoneal dialysis patients accompanied with hypoproteinemia are more likely to have inflammation complications and cardiovascular diseases,which should cause more attention on their malnutrition-inflammation- CVD(MIA)syndrome diagnosis and treatment.
