中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
12期
1614-1616
,共3页
脑电双频指数%丙泊酚%靶控输注
腦電雙頻指數%丙泊酚%靶控輸註
뇌전쌍빈지수%병박분%파공수주
Bispectral index%Propofol%Target controlled infusion
目的 探讨脑电双频指数(BIS)在未插管全麻中麻醉深度监测的应用价值.方法 选择局麻下手术患者60例,随机均分为Ⅰ、Ⅱ、Ⅲ组,分别靶控输注(TCI)丙泊酚1.0、1.5、2.0μg/ml.分别于手术开始前10 min(T0)、局部阻滞麻醉(T1)、手术开始30 min(T2)、手术开始60 min(T3)及手术结束时(T4)记录心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2)、脑电双频指数(BIS)值和改良清醒镇静(MOAA/S)评分.结果 BIS值随MOAA/S评分下降而下降;Ⅲ组术中各时点的MOAA/S评分均低于Ⅰ组(均P<0.05),但术中3例出现呼吸抑制;Ⅱ、Ⅲ组MAP在MOAA/S评分3～2时下降有统计学意义(P<0.05).结论 在未插管全麻中,采用丙泊酚1.0～1.5μg/ml TCI镇静较为合适.
目的 探討腦電雙頻指數(BIS)在未插管全痳中痳醉深度鑑測的應用價值.方法 選擇跼痳下手術患者60例,隨機均分為Ⅰ、Ⅱ、Ⅲ組,分彆靶控輸註(TCI)丙泊酚1.0、1.5、2.0μg/ml.分彆于手術開始前10 min(T0)、跼部阻滯痳醉(T1)、手術開始30 min(T2)、手術開始60 min(T3)及手術結束時(T4)記錄心率(HR)、平均動脈壓(MAP)、血氧飽和度(SpO2)、腦電雙頻指數(BIS)值和改良清醒鎮靜(MOAA/S)評分.結果 BIS值隨MOAA/S評分下降而下降;Ⅲ組術中各時點的MOAA/S評分均低于Ⅰ組(均P<0.05),但術中3例齣現呼吸抑製;Ⅱ、Ⅲ組MAP在MOAA/S評分3～2時下降有統計學意義(P<0.05).結論 在未插管全痳中,採用丙泊酚1.0～1.5μg/ml TCI鎮靜較為閤適.
목적 탐토뇌전쌍빈지수(BIS)재미삽관전마중마취심도감측적응용개치.방법 선택국마하수술환자60례,수궤균분위Ⅰ、Ⅱ、Ⅲ조,분별파공수주(TCI)병박분1.0、1.5、2.0μg/ml.분별우수술개시전10 min(T0)、국부조체마취(T1)、수술개시30 min(T2)、수술개시60 min(T3)급수술결속시(T4)기록심솔(HR)、평균동맥압(MAP)、혈양포화도(SpO2)、뇌전쌍빈지수(BIS)치화개량청성진정(MOAA/S)평분.결과 BIS치수MOAA/S평분하강이하강;Ⅲ조술중각시점적MOAA/S평분균저우Ⅰ조(균P<0.05),단술중3례출현호흡억제;Ⅱ、Ⅲ조MAP재MOAA/S평분3～2시하강유통계학의의(P<0.05).결론 재미삽관전마중,채용병박분1.0～1.5μg/ml TCI진정교위합괄.
Objective To investigate the utility of anesthesia depth monitoring of BIS during general anesthesia without tracheal intubation.Methods Sixty patients underwent surgery with local anesthesia were randomly divided into three groups of Ⅰ ,Ⅱand Ⅲ,who were sedated with propofol by TCI propofol 1.0,1.5,2.0μg/ml,respectively.HR,MAP,SpO2 BIS and MOAA/S score were recorded at l0min before operation(T0) .during local anesthesia ( T1) , at 30min after incision (T2) , at 60min after incision (T3) , and the end of operation (T4).Results BIS values declined with the decrease of MOAA/S.MOAA/S score was lower in group Ⅲ than that in group Ⅰ (all P < 0.05).Respiratory depression was seen in 3 cases in group Ⅲ.The difference of MAP had statistical significance between level 3 and level 2 of MOAA/S in group Ⅱ and group Ⅲ (P < 0.05).Conclusion Propofol 1.0 ～ 1.5 μg/ml given by TCI could produce optimal depth of sedation with less side effects in surgery during local anesthesia.
