CAJ | 학술논문

为了比较环磷酰胺(CTX)大剂量冲击疗法和隔日小剂量连续给药法对难治性肾病综合征(NS)的疗效，我们对90例成人难治性NS按两种不同方案给予治疗。结果表明：两种方案治疗均能使病人24h尿蛋白量降低、血清白蛋白值升高，以CTX冲击治疗组变化更明显(P＜0.01)；冲击治疗组未出现副作用。结论：冲击治疗法明显优于小剂量连续给药法。
위료비교배린선알(CTX)대제량충격요법화격일소제량련속급약법 대난치성신병종합정(NS)적료효，아문대90례성인난치성NS안량충불동방안급여치료。결과 표명：량충방안치료균능사병인24h뇨단백량강저、혈청백단백치승고，이CTX충격치료조 변화경명현(P＜0.01)；충격치료조미출현부작용。결론：충격치요법명현우우소제량 련속급약법。
We observated the effect which 90 case s resistant nephrotic s yndrome (NS) were treated by high-dose pulse therapy and low dose continue thera py of cyclophosphamide (CTX).Results:Two regimen therapy both albuminin serum had risen to some degree and 24-hour ur inary protein had decreased,these alterations were more significantly(P＜0.01) i n pulse therapy subject.Conclusions:The high-dose pulse therapy of CTX was apparent excel to low-dose continue therapy