CAJ | 학술논문

目的系统地研究五加属植物细柱五加皮Acanthopanax gracilistylus 的化学成分.方法用热甲醇分别对细柱五加皮的根进行提取后,采用Diaion HP-20P,Chromatorex ODS,Sephadex LH-20和硅胶色谱进行分离纯化,通过光谱分析以及直接和标准品对照进行结构确认.结果从根皮中得到二萜类等6 个化合物:五加酸(Ⅰ),异贝壳杉烯酸(Ⅱ),l-芝麻素(Ⅲ),豆甾醇(Ⅳ),β-谷甾醇(Ⅴ)和刺五加苷B(Ⅵ).结论化合物Ⅰ,Ⅳ,Ⅴ为首次从该植物中分离得到.
목적계통지연구오가속식물세주오가피Acanthopanax gracilistylus 적화학성분.방법용열갑순분별대세주오가피적근진행제취후,채용Diaion HP-20P,Chromatorex ODS,Sephadex LH-20화규효색보진행분리순화,통과광보분석이급직접화표준품대조진행결구학인.결과종근피중득도이첩류등6 개화합물:오가산(Ⅰ),이패각삼희산(Ⅱ),l-지마소(Ⅲ),두치순(Ⅳ),β-곡치순(Ⅴ)화자오가감B(Ⅵ).결론화합물Ⅰ,Ⅳ,Ⅴ위수차종해식물중분리득도.
Object To study the chemical constituents of Acanthopanax gracilistylus W. W. Smith as the purpose of study continually on plants of Acanthopanax (Decne. et Planch.) Miq. Methods The leaves, roots, and stem barks of A. gracilistylus were extracted with hot MeOH and steam distillation respectively, and then, separated and purified by column chromatographies on Diaion HP-20P, Chromatorex ODS, Sephadex LH-20 and silica gel. All compounds were identified on the basis of chemical and spectral analysis including GC-MS, 1D and 2D NMR, MS and IR, or comparison with the reported data. Results Six compounds were obtained from the roots of A. gracilistylus. They are (-)-pimara-9 (11), 15-dien-19-oic acid (Ⅰ), (-)-kaur-16-en-19-oic acid (Ⅱ), d-sesamin (Ⅲ), stigmasterol (Ⅳ), β-sitosterol (Ⅴ), and eleutheroside B (Ⅵ). Conclusion Compounds Ⅰ, Ⅳ, and Ⅴ are obtained from this plant for the first time.