CAJ | 학술논문

目的探讨噬血细胞综合征生化免疫指标的改变及临床意义.方法分别应用免疫荧光法和酶联免疫法,对噬血细胞综合征患儿及同期普通呼吸道感染患儿静脉血进行生化及免疫指标检测.结果实验组患儿转氨酶、乳酸脱氢酶、胆红素、甘油三酯、血清铁蛋白、β2微球蛋白明显增高,纤维蛋白原、白蛋白明显降低等较对照组差异有统计学意义(P<0.05).结论噬血细胞综合征患儿部分生化及免疫指标有明显变化,对明确诊断及进一步采取针对性治疗有很大意义.
목적 탐토서혈세포종합정생화면역지표적개변급림상의의.방법 분별응용면역형광법화매련면역법,대서혈세포종합정환인급동기보통호흡도감염환인정맥혈진행생화급면역지표검측.결과 실험조환인전안매、유산탈경매、담홍소、감유삼지、혈청철단백、β2미구단백명현증고,섬유단백원、백단백명현강저등교대조조차이유통계학의의(P<0.05).결론 서혈세포종합정환인부분생화급면역지표유명현변화,대명학진단급진일보채취침대성치료유흔대의의.
Objective To investigate the change of the biochemistry and immunity indexes in the children with hemophagocytic syndrome and its clinical significance. Methods The immunofluorescence and enzyme immuno assay methods were applied for detecting the biochemistry and immunity indexes of vein blood specimens from the children with hemophagocytic syndrome (the experiment group) and the ones with ordinary respiratory tract infection (the comparison group) respectively.Results Compared with the comparison group GPT、GOT、LDH、TBIL、TG、FP and β2-PG of the experiment group increased, in the same time, FIB and ALB reduced(P<0.05).Conclusion Some biochemistry and immunity indexes have obvious changes in children with hemophagocytic syndrome,it is significant to diagnose and take pertinent therapy for this disease.