现代口腔医学杂志
現代口腔醫學雜誌
현대구강의학잡지
JOURNAL OF MODERN STOMATOLOGY
2010年
2期
90-92
,共3页
王左敏%李一梓%庞宝森%王辰
王左敏%李一梓%龐寶森%王辰
왕좌민%리일재%방보삼%왕신
IL-20%牙周炎%COPD
IL-20%牙週炎%COPD
IL-20%아주염%COPD
IL-20%Periodontitis%COPD
目的 初步探讨血清白细胞介素20(IL-20)及白细胞介素6(IL-6)、肿瘤坏死因子(TNF-α)在牙周炎及慢性阻塞性肺疾病(COPD)中的作用.方法 选取151例患者,按牙周炎及COPD的严重程度分为四组,采用酶联免疫吸附法(ELISA)测定四组患者血清中IL-20、IL-6和TNF-α的浓度.结果 中重度牙周炎伴COPD患者血清中IL-20、IL-6和TNF-α的水平显著高于对照人群,并且两种疾病并存时,血清IL-20水平较单独存在时高.结论 血清中IL-20及IL-6、TNF-α水平的高表达可能与牙周炎及COPD的发病机理有关,加重两种疾病炎症反应过程.
目的 初步探討血清白細胞介素20(IL-20)及白細胞介素6(IL-6)、腫瘤壞死因子(TNF-α)在牙週炎及慢性阻塞性肺疾病(COPD)中的作用.方法 選取151例患者,按牙週炎及COPD的嚴重程度分為四組,採用酶聯免疫吸附法(ELISA)測定四組患者血清中IL-20、IL-6和TNF-α的濃度.結果 中重度牙週炎伴COPD患者血清中IL-20、IL-6和TNF-α的水平顯著高于對照人群,併且兩種疾病併存時,血清IL-20水平較單獨存在時高.結論 血清中IL-20及IL-6、TNF-α水平的高錶達可能與牙週炎及COPD的髮病機理有關,加重兩種疾病炎癥反應過程.
목적 초보탐토혈청백세포개소20(IL-20)급백세포개소6(IL-6)、종류배사인자(TNF-α)재아주염급만성조새성폐질병(COPD)중적작용.방법 선취151례환자,안아주염급COPD적엄중정도분위사조,채용매련면역흡부법(ELISA)측정사조환자혈청중IL-20、IL-6화TNF-α적농도.결과 중중도아주염반COPD환자혈청중IL-20、IL-6화TNF-α적수평현저고우대조인군,병차량충질병병존시,혈청IL-20수평교단독존재시고.결론 혈청중IL-20급IL-6、TNF-α수평적고표체가능여아주염급COPD적발병궤리유관,가중량충질병염증반응과정.
Objective This study was to detect and to analyse serum IL-20, IL-6 and TNF-α levels in patients with PD or/and COPD.Methods A total of 151 clinical patients were selected and divided into four groups according to the degrees of periodontitis and COPD. Serum IL-20 and IL-6, TNF-α levels were detected by ELISA.Results Serum levels of IL-20 and IL-6, TNF-α were significantly higher in patients with moderate and sever PD or patients with COPD than those of their respective controls. And it was highest in patients with the two diseases.Conclusion High levels of serum IL-20 and IL-6, TNF-α may be involved in the mechanism of relationship between periodontitis and COPD and sharpen the process of two disease.
