中华全科医师杂志
中華全科醫師雜誌
중화전과의사잡지
CHINESE JOURNAL OF GENERAL PRACTITIONERS
2008年
2期
83-85
,共3页
肺疾病%阻塞性%睡眠呼吸暂停综合征%生活质量%存活率
肺疾病%阻塞性%睡眠呼吸暫停綜閤徵%生活質量%存活率
폐질병%조새성%수면호흡잠정종합정%생활질량%존활솔
Lung diseases,obstructive%Sleep apnea syndromes%Quality of life%Survival rate
目的 分析慢性阻塞性肺疾病(COPD)合并阻塞性睡眠呼吸暂停低通气综合征(重叠综合征,OS)的临床指标.方法 对8例重叠综合征患者(OS组)及10例单纯COPD患者(COPD组)3年期间急性发作次数、发作程度、生存质量、运动耐力、并发症、3年存活率进行研究.结果 无论是生存质量还是运动耐力OS组均低于COPD组(P＜0.05),而且每年急性发作次数OS组较COPD组多(P＜0.05),发作程度亦较COPD组高(P＜0.05),3年存活率较COPD组低.OS组并发高血压、糖尿病、红细胞增多症、呼吸衰竭和心力衰竭者比例均较COPD组高,以急性发作次数增多最为明显.结论 重叠综合征较单纯COPD危害性更大,须引起人们高度重视.夜间睡眠时吸氧不能提高其生存时间,使用双水平气道正压或持续气道正压通气再辅以吸氧可能取得良好疗效.
目的 分析慢性阻塞性肺疾病(COPD)閤併阻塞性睡眠呼吸暫停低通氣綜閤徵(重疊綜閤徵,OS)的臨床指標.方法 對8例重疊綜閤徵患者(OS組)及10例單純COPD患者(COPD組)3年期間急性髮作次數、髮作程度、生存質量、運動耐力、併髮癥、3年存活率進行研究.結果 無論是生存質量還是運動耐力OS組均低于COPD組(P＜0.05),而且每年急性髮作次數OS組較COPD組多(P＜0.05),髮作程度亦較COPD組高(P＜0.05),3年存活率較COPD組低.OS組併髮高血壓、糖尿病、紅細胞增多癥、呼吸衰竭和心力衰竭者比例均較COPD組高,以急性髮作次數增多最為明顯.結論 重疊綜閤徵較單純COPD危害性更大,鬚引起人們高度重視.夜間睡眠時吸氧不能提高其生存時間,使用雙水平氣道正壓或持續氣道正壓通氣再輔以吸氧可能取得良好療效.
목적 분석만성조새성폐질병(COPD)합병조새성수면호흡잠정저통기종합정(중첩종합정,OS)적림상지표.방법 대8례중첩종합정환자(OS조)급10례단순COPD환자(COPD조)3년기간급성발작차수、발작정도、생존질량、운동내력、병발증、3년존활솔진행연구.결과 무론시생존질량환시운동내력OS조균저우COPD조(P＜0.05),이차매년급성발작차수OS조교COPD조다(P＜0.05),발작정도역교COPD조고(P＜0.05),3년존활솔교COPD조저.OS조병발고혈압、당뇨병、홍세포증다증、호흡쇠갈화심력쇠갈자비례균교COPD조고,이급성발작차수증다최위명현.결론 중첩종합정교단순COPD위해성경대,수인기인문고도중시.야간수면시흡양불능제고기생존시간,사용쌍수평기도정압혹지속기도정압통기재보이흡양가능취득량호료효.
Objective To analyze the clinical features of overlap syndromes(OS),I.e.,chronic obstructive pulmonary disease(COPD)complicated with obstructive sleep apnea hypoventilation syndrome (OSAHS).Methods Frequency of episodes of acute exacerbation,severity,quality of life,exercise endurance,complications and three-year survival rate were investigated in eight patients with OS and 10 patients with pure COPD.Results Both quality of life and exercise endurance in OS group were lower than those in COPD group(P＜0.05).Annual frequency of acute exacerbation episodes and severity were more and three-year survival rate was lower in OS group than those in COPD group(P＜0.05).Complications of hypertension,diabetes,erythrocythemia,respiratory failure and heart failure were all more frequent in OS group than those in COPD group.Among all the above clinical features,increased frequency of acute exacerbation episodes was the most significant.Conclusions OS is clinically more severe than pure COPD,so more attention should be paid to it.Survival for patients with OS can not extended by nocturnal oxygen therapy alone,which may be beneficial when combined with biphasic positive airway pressure(BiPAP)or continuous positive airway pressure(CPAP)ventilation.
