CAJ | 학술논문

目的评价动态增强磁共振成像在VX2兔肿瘤转移性、炎性增生性淋巴结鉴别诊断中的价值.方法 20只健康新西兰大白兔随机分为肿瘤转移性淋巴结组、炎性增生性淋巴结组,每组10只.对两组淋巴结分别进行动态增强磁共振成像.结果 9个肿瘤转移性淋巴结及9个炎性增生性淋巴结成功进行动态增强磁共振成像.肿瘤转移性淋巴结组时间信号曲线以速升平台型为主,峰值增强率、峰值时间、最大强化速率分别为284％±125％、(118±47)s和(6.5±2.7)％/s；而炎性增生性淋巴结组时间信号曲线以持续上升型为主,峰值增强率、峰值时间、最大强化速率分别为199％±109％、(143±40)s和(3.6±1.5)％/s,二者比较差异有统计学意义(P＜0.05).结论动态增强磁共振成像可准确反映VX2兔肿瘤转移性及炎性增生性淋巴结的血流动力学特征并对其进行鉴别诊断.
목적 평개동태증강자공진성상재VX2토종류전이성、염성증생성림파결감별진단중적개치.방법 20지건강신서란대백토수궤분위종류전이성림파결조、염성증생성림파결조,매조10지.대량조림파결분별진행동태증강자공진성상.결과 9개종류전이성림파결급9개염성증생성림파결성공진행동태증강자공진성상.종류전이성림파결조시간신호곡선이속승평태형위주,봉치증강솔、봉치시간、최대강화속솔분별위284％±125％、(118±47)s화(6.5±2.7)％/s；이염성증생성림파결조시간신호곡선이지속상승형위주,봉치증강솔、봉치시간、최대강화속솔분별위199％±109％、(143±40)s화(3.6±1.5)％/s,이자비교차이유통계학의의(P＜0.05).결론 동태증강자공진성상가준학반영VX2토종류전이성급염성증생성림파결적혈류동역학특정병대기진행감별진단.
Objective To study the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI ) features of VX2 rabbits carcinoma metastatic and inflammatory lymph nodes.Methods Twenty healthy adult New Zealand white rabbits were divided into metastatic lymph node group and inflammatory lymph node group randomly. There were ten rabbits in each group. All 20 rabbits underwent DCE-MRI.Peak enhancement,time to peak,maximum slope and signal intensity versus time curves were generated from each node individually.Results DCE-MRI were obtained for nine cases of metastatic lymph nodes and nine cases of inflammatory lymph nodes.The signal intensity versus time curves of metastatic lymph nodes were appeared as rapid ascending and plateauing,and peak enhancement,time to peak,maximum slope of metastatic lymph nodes group were 284％ ± 125％,(118 ±47) s and (6.5 ±2.7) ％/s,respectively.The signal intensity versus time curves of inflammatory lymph nodes were appeared as insisting ascending,and peak enhancement,time to peak,maximum slope of inflammatory lymph nodes group were 199％ ± 109％,( 143 ± 40) s and ( 3.6 ± 1.5 ) ％/s,respectively.There was significantly higher peak enhancement,shorter time to peak and higher maximum slope in the metastatic lymph nodes group compared with the inflammatory lymph nodes group (P ＜ 0.05 ). Conclusions DCE-MRI can accurately reflect the hemodynamic characteristics of VX2 rabbits neoplasm metastatic lymph nodes and inflammatory lymph nodes,and can differentiate VX2 rabbits neoplasm metastatic lymph nodes from inflammatory lymph nodes.