CAJ | 학술논문

目的 2型糖尿病患者进行有规律的中等强度的运动疗法,观察运动前后血糖、胰岛素水平及其曲线下面积、血脂、体重指数(BMI)、微量尿白蛋白等项的变化.方法 28例患者平均年龄59.0±7.6岁,在饮食和口服降糖药物治疗的同时,每日坚持1～1.5小时保持中等负荷强度的运动疗法,历时12个月,观察运动前后上述各项指标的变化,并随机与40例、平均年龄59.5±7.3岁,以饮食和口服降糖药物治疗为主的2型糖尿病患者作对照.结果运动组的血糖及其曲线下面积、HbAlc、肥胖型患者的BMI均有明显降低(P＜0.01),均明显优于对照组(P＜0.01).空腹及餐后2、3小时血浆胰岛素水平亦下降(P＜0.05).运动疗法对微量尿白蛋白的排出无影响(P＞0.05).结论运动疗法能明显降低2型糖尿病患者的血糖和肥胖者的体重指数,改善血脂代谢,降低胰岛素抵抗,恢复胰岛素的敏感性,其作用是单纯药物和饮食疗法不能代替的.
목적 2형당뇨병환자진행유규률적중등강도적운동요법,관찰운동전후혈당、이도소수평급기곡선하면적、혈지、체중지수(BMI)、미량뇨백단백등항적변화.방법 28례환자평균년령59.0±7.6세,재음식화구복강당약물치료적동시,매일견지1～1.5소시보지중등부하강도적운동요법,력시12개월,관찰운동전후상술각항지표적변화,병수궤여40례、평균년령59.5±7.3세,이음식화구복강당약물치료위주적2형당뇨병환자작대조.결과운동조적혈당급기곡선하면적、HbAlc、비반형환자적BMI균유명현강저(P＜0.01),균명현우우대조조(P＜0.01).공복급찬후2、3소시혈장이도소수평역하강(P＜0.05).운동요법대미량뇨백단백적배출무영향(P＞0.05).결론운동요법능명현강저2형당뇨병환자적혈당화비반자적체중지수,개선혈지대사,강저이도소저항,회복이도소적민감성,기작용시단순약물화음식요법불능대체적.
Objective To observe the changes of type 2 diabetes mellitus patients in blood sugar,TC,TG,HDL C,plasma insulin,body mass index(BMI), microalbuminuria,etc before and after moderate intensity exercise training.Methods 28 patients with mean age of 59.0±7.6 years did moderate intensity exercise training for 1～1.5 hours every day for 12 month.At the same time they received the treatment of diet and oral antidiabetic drug com pared with 40 controls without exercise training. Before and after the observing period we measured the values of items above.Results Plasma glucose level , HbAlc,AUCGS(the area under the curve of glucose sugar) and BMI in fat diabetes with training team were obviously decreased compared with those before observation( P <0.01) . There were significant difference between two groups in the above( P <0.01). The amount of fasting insulin, 2h insulin and 3h insulin descended in training group( P <0.05). Exercise training had no effect on urinary albumin excretion( P >0.05).Conclusion Exercise training can significantly descend blood sugar, insulin resistance and BMI of obese people ,improve lipidmetabolism and ascend insulin sensitivity. So the action of exercise can’t be replaced by the diet and oral drug.