CAJ | 학술논문

目的巩固基本消除丝虫病的成果,了解基本消除丝虫病后的流行动态和传播规律,为消灭丝虫病提供科学依据.方法在65个原丝虫病流行县开展病原学、蚊媒、血清学纵向和横向监测.结果 65个县(市)连续13～23年的横向监测显示,已连续7～23年未发现微丝蚴阳性者,蚊媒监测9-23年无人体幼丝虫感染.65个县(市)中有41个县(市)基本消除丝虫病后10年内的监测乡和人口覆盖率分别为43.65%和5.08%,10年后再监测的监测乡和人口覆盖率分别为15.96%和1.25%;24个县(市)基本消除后10年以上病原学监测乡和人口覆盖率分别为39.14%和3.94%.11个纵向监测点观察13～20年,发现的14例残存微丝蚴血症者,在未采取治疗措施的情况下,均于次年转阴.血清学(IFAT)监测人群抗体水平已和非流行区人群相近.结论浙江省丝虫病传播已被阻断,已实现全省消除丝虫病.
목적 공고기본소제사충병적성과,료해기본소제사충병후적류행동태화전파규률,위소멸사충병제공과학의거.방법 재65개원사충병류행현개전병원학、문매、혈청학종향화횡향감측.결과 65개현(시)련속13～23년적횡향감측현시,이련속7～23년미발현미사유양성자,문매감측9-23년무인체유사충감염.65개현(시)중유41개현(시)기본소제사충병후10년내적감측향화인구복개솔분별위43.65%화5.08%,10년후재감측적감측향화인구복개솔분별위15.96%화1.25%;24개현(시)기본소제후10년이상병원학감측향화인구복개솔분별위39.14%화3.94%.11개종향감측점관찰13～20년,발현적14례잔존미사유혈증자,재미채취치료조시적정황하,균우차년전음.혈청학(IFAT)감측인군항체수평이화비류행구인군상근.결론 절강성사충병전파이피조단,이실현전성소제사충병.
Objective To observe the dynamics of prevalence and the regularity of transmission after that filariasis has been basically eliminated and to provide scientific evidence for the program framed to finally elirrinate filarisis in Zhejiang province. Methods A cross-sectional and longitudinal survey with parasitologicai, entomological and serological methods were extensively carried out from 1997 to 2000 in 65 counties where filariasis were previously endemic Results In 65 counties, cross-sectional surveillance on the disease has continuously been conducted for 13-23 years. The results showed that microfilaremia cases had not been found for 7-23 years, and filaria larvae had failed to detect from mosquito vectors for 9-23 years. In 41 ones of 65 counties, the surveillance covering rates of township, populations were 43.65% and 5.08%, respectively,in the first ten years, whereas in the following ten years the covering rates of township, populations were 15.96% and 1.25%, respectively. For the more ten years' parasitological surveillance of 24 counties where the disease had been basically eliminated, the covering rates of township, populations were 39.14% and 3.94%, respectively. The results of the 13-20 years'observation of 11 longitudinal surveillance sites showed that 14 micrfilaremia cases could turned to be negative next year without treatment. There was no significant difference between the levels of filaria antibody of inhabitants both living in endemic and in non-endemic area. Conclusion The transmission of filariasis in Zhejiang province has been interrupted and filariasis has been eliminated.