CAJ | 학술논문

目的探讨多普勒组织成像(DTI)结合多巴酚丁胺负荷超声心动图(DSE)评价无症状性心肌缺血患者左室局部与整体舒张功能的价值.方法 30例无症状性心肌缺血患者及正常人30例均行DSE,DTI在静息和负荷下于左房室瓣环、左室壁基底段、中间段取样,测量舒张功能参数:舒张早期速度(Ve),舒张晚期速度(Va),E峰减速时问(Te).结果随着多巴酚丁胺药物剂量的增加,正常组峰值速度均逐渐增加,峰值速度运动时间逐渐缩短,大剂量时Ve/Va比值略有下降,差异无统计学意义;无症状性心肌缺血组峰值速度小剂量负荷时增加,大剂量时则下降,峰值速度运动时间呈逐渐缩短趋势,Ve/Va比值均显著降低,两组间各指标相比差异有统计学意义(P<0.05).结论 DTI技术与DSE结合可定量评价无症状性心肌缺血患者左室局部与整体舒张功能.
목적 탐토다보륵조직성상(DTI)결합다파분정알부하초성심동도(DSE)평개무증상성심기결혈환자좌실국부여정체서장공능적개치.방법 30례무증상성심기결혈환자급정상인30례균행DSE,DTI재정식화부하하우좌방실판배、좌실벽기저단、중간단취양,측량서장공능삼수:서장조기속도(Ve),서장만기속도(Va),E봉감속시문(Te).결과 수착다파분정알약물제량적증가,정상조봉치속도균축점증가,봉치속도운동시간축점축단,대제량시Ve/Va비치략유하강,차이무통계학의의;무증상성심기결혈조봉치속도소제량부하시증가,대제량시칙하강,봉치속도운동시간정축점축단추세,Ve/Va비치균현저강저,량조간각지표상비차이유통계학의의(P<0.05).결론 DTI기술여DSE결합가정량평개무증상성심기결혈환자좌실국부여정체서장공능.
Objective To evaluate left ventricle partial and global diastolic function in patients with silent myocardial ischemia (SMI) by Doppler tissue imaging (DTI) combined with dobutamine stress echocardiography (DSE).Methods 30 cases of silent myocardial ischemia(SMI) and 30 cases of normal control underwent dobu-tamine stress echocardiography(DSE). DTI was acquired at baseline and stress, and waveforms in mitral valve clos- ing, and the base and mid segments of left ventricle were used to measure diastolic early velocity(Ve), diastolic lately velocity(Va) ,and E deceleration time(Te). Results Ⅴ in control group increased accompanied with the increasing dose of dobutamine, Ve/Va decreased a little but not significantly. Ⅴ in the group with silent myocardial ischemia (SMI) increased at 10μg·kg-1·min-1 ,but decreased at 40μg·kg-1·min-1 compared with 10μg·kg-1·min-1 ,T in both control and DSE group decreased at 40μg/kg accompanied with 10μg·kg-1·min-1, T in both control and DSE group decreased accompanied with the increasing dose of dobutamine, and there were significant differences between the groups(P < 0.05). Conclusion DTI-DSE could quantificadvely detect the partial and global diastolic function of left ventricle.